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The cellular metabolic process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. The process whereby new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. The process by which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases. The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication. The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: DNA unwinding involved in replication
Acc: GO:0006268
Aspect: Biological Process
Desc: The process by which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
Synonyms:
  • DNA unwinding during replication
  • DNA unwinding factor
Proteins in PDR annotated with:
   This term: 92 [Search]
   Term or descendants: 92 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006268 - DNA unwinding involved in replication (interactive image map)
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