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The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA. The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives. The cellular chemical reactions and pathways involving nucleobases, nucleosides and nucleotides. The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base. The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J. The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA. Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine bases. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine bases. The chemical reactions and pathways resulting in the formation of pyrimidine bases, 1,3-diazine, organic nitrogenous bases. The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidines. The chemical reactions and pathways involving pyrimidine bases, 1,3-diazine, organic nitrogenous bases. The chemical reactions and pathways resulting in the breakdown of pyrimidine bases, 1,3-diazine, organic nitrogenous bases. The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: pyrimidine base metabolic process
Acc: GO:0006206
Aspect: Biological Process
Desc: The chemical reactions and pathways involving pyrimidine bases, 1,3-diazine, organic nitrogenous bases.
Synonyms:
  • pyrimidine metabolism
  • pyrimidine metabolic process
  • pyrimidine base metabolism
Proteins in PDR annotated with:
   This term: 20 [Search]
   Term or descendants: 130 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006206 - pyrimidine base metabolic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle