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A protein complex that possesses alpha-ketoglutarate dehydrogenase activity. The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity. Any of the heteromeric enzymes that act in the TCA cycle. Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mitochondrial alpha-ketoglutarate dehydrogenase complex
Acc: GO:0005947
Aspect: Cellular Component
Desc: Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.
Synonyms:
  • 2-oxoglutarate dehydrogenase complex
Proteins in PDR annotated with:
   This term: 7 [Search]
   Term or descendants: 7 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005947 - mitochondrial alpha-ketoglutarate dehydrogenase complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle