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Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. An organelle lumen that is part of an intracellular organelle. The volume enclosed by the membranes of the rough endoplasmic reticulum. An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane. The volume enclosed by the membranes of the smooth endoplasmic reticulum. The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. The volume enclosed by the membranes of the sarcoplasmic reticulum. The volume enclosed by the membranes of the endoplasmic reticulum. A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: endoplasmic reticulum lumen
Acc: GO:0005788
Aspect: Cellular Component
Desc: The volume enclosed by the membranes of the endoplasmic reticulum.
Synonyms:
  • ER cisterna
  • endoplasmic reticulum cisterna
  • cisternal lumen
  • ER lumen
  • GO:0016022
Proteins in PDR annotated with:
   This term: 126 [Search]
   Term or descendants: 134 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005788 - endoplasmic reticulum lumen (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle