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Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate. An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. It is also involved in the functioning of other transmembrane channels. null Catalysis of the transfer of a negatively charged ion from one side of a membrane to the other. Catalysis of the transmembrane transfer of a chloride ion by a voltage-gated channel. Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts. Catalysis of the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts. Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Catalysis of facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Catalysis of the energy-independent passage of anions across a lipid bilayer down a concentration gradient. Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: chloride channel activity
Acc: GO:0005254
Aspect: Molecular Function
Desc: Catalysis of facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
Proteins in PDR annotated with:
   This term: 115 [Search]
   Term or descendants: 208 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005254 - chloride channel activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle