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Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP. Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His). Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate, to form aminoacyl-tRNA or a related compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: histidine-tRNA ligase activity
Acc: GO:0004821
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).
Synonyms:
  • histidyl-tRNA synthetase activity
  • histidine translase activity
  • histidyl-transfer ribonucleate synthetase activity
  • L-histidine:tRNAHis ligase (AMP-forming)
Proteins in PDR annotated with:
   This term: 33 [Search]
   Term or descendants: 33 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004821 - histidine-tRNA ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle