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The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, including expression of the surrogate light chain, association of the surrogate light chain with heavy chain, and expression of the complete pre-B cell receptor on the cell surface. Expression of a single heavy chain allele during pre-B cell differentiation. The process whereby a precursor cell type acquires the specialized features of a B cell. The process whereby a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments. The process whereby a precursor cell type acquires the specialized features of an immature B cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: pre-B cell differentiation
Acc: GO:0002329
Aspect: Biological Process
Desc: The process whereby a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
Synonyms:
  • pre-B lymphocyte differentiation
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 3 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0002329 - pre-B cell differentiation (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle