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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.729001666405]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription factor TFIID complex 5.3053E-6 2 15 2 6292
DNA-directed RNA polymerase II, holoenzyme 7.7811E-5 2 56 2 6292
transcription factor complex 1.2556E-4 2 71 2 6292
transcription factor TFIIIB complex 9.5344E-4 2 3 1 6292
nucleoplasm part 1.5102E-3 2 245 2 6292
nucleoplasm 1.7541E-3 2 264 2 6292
RNA polymerase I transcription factor complex 2.859E-3 2 9 1 6292
SLIK (SAGA-like) complex 5.0798E-3 2 16 1 6292
nuclear lumen 5.1728E-3 2 453 2 6292
SAGA complex 6.9813E-3 2 22 1 6292
SAGA-type complex 7.2981E-3 2 23 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription initiation from RNA polymerase II promoter 5.4619E-5 2 47 2 6292
transcription initiation 8.3521E-5 2 58 2 6292
protein complex biogenesis 6.0304E-4 2 155 2 6292
protein complex assembly 6.0304E-4 2 155 2 6292
macromolecular complex assembly 1.9877E-3 2 281 2 6292
transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
macromolecular complex subunit organization 3.2108E-3 2 357 2 6292
transcription initiation from RNA polymerase III promoter 3.4937E-3 2 11 1 6292
cellular component assembly 3.7349E-3 2 385 2 6292
regulation of transcription involved in G1 phase of mitotic cell cycle 4.4455E-3 2 14 1 6292
transcription, DNA-dependent 6.3792E-3 2 503 2 6292
RNA biosynthetic process 6.5067E-3 2 508 2 6292
transcription 7.6839E-3 2 552 2 6292
G1 phase of mitotic cell cycle 8.5646E-3 2 27 1 6292
G1 phase 8.5646E-3 2 27 1 6292
transcription from RNA polymerase I promoter 9.5139E-3 2 30 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

general RNA polymerase II transcription factor activity 1.0186E-4 2 64 2 6292
RNA polymerase II transcription factor activity 4.2367E-4 2 130 2 6292
protein homodimerization activity 6.3568E-4 2 2 1 6292
identical protein binding 9.5344E-4 2 3 1 6292
protein dimerization activity 1.9064E-3 2 6 1 6292
transcription regulator activity 2.8947E-3 2 339 2 6292
RNA polymerase I transcription factor activity 3.1764E-3 2 10 1 6292
RNA polymerase III transcription factor activity 3.1764E-3 2 10 1 6292
DNA bending activity 4.1283E-3 2 13 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle