From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.73068122918] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
pore complex | 6.6999E-5 | 2 | 52 | 2 | 6292 |
nuclear pore | 6.6999E-5 | 2 | 52 | 2 | 6292 |
nuclear envelope | 9.9543E-4 | 2 | 199 | 2 | 6292 |
integral to membrane | 1.6363E-3 | 2 | 255 | 2 | 6292 |
intrinsic to membrane | 1.7276E-3 | 2 | 262 | 2 | 6292 |
COPII vesicle coat | 2.5415E-3 | 2 | 8 | 1 | 6292 |
ER to Golgi transport vesicle membrane | 2.5415E-3 | 2 | 8 | 1 | 6292 |
endomembrane system | 3.9918E-3 | 2 | 398 | 2 | 6292 |
transport vesicle membrane | 4.7627E-3 | 2 | 15 | 1 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
ER to Golgi transport vesicle | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear pore organization | 1.9099E-5 | 2 | 28 | 2 | 6292 |
nucleus organization | 7.7811E-5 | 2 | 56 | 2 | 6292 |
membrane budding | 1.5888E-3 | 2 | 5 | 1 | 6292 |
cellular macromolecular complex subunit organization | 1.6882E-3 | 2 | 259 | 2 | 6292 |
macromolecular complex subunit organization | 3.2108E-3 | 2 | 357 | 2 | 6292 |
ribosomal protein import into nucleus | 7.2981E-3 | 2 | 23 | 1 | 6292 |
snRNP protein import into nucleus | 7.2981E-3 | 2 | 23 | 1 | 6292 |
snRNA export from nucleus | 7.2981E-3 | 2 | 23 | 1 | 6292 |
NLS-bearing substrate import into nucleus | 7.2981E-3 | 2 | 23 | 1 | 6292 |
snRNA transport | 7.2981E-3 | 2 | 23 | 1 | 6292 |
intracellular transport | 7.7118E-3 | 2 | 553 | 2 | 6292 |
mRNA-binding (hnRNP) protein import into nucleus | 7.9314E-3 | 2 | 25 | 1 | 6292 |
rRNA export from nucleus | 8.5646E-3 | 2 | 27 | 1 | 6292 |
rRNA transport | 8.5646E-3 | 2 | 27 | 1 | 6292 |
tRNA export from nucleus | 8.8811E-3 | 2 | 28 | 1 | 6292 |
tRNA transport | 8.8811E-3 | 2 | 28 | 1 | 6292 |
establishment of localization in cell | 9.0494E-3 | 2 | 599 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
structural molecule activity | 2.8947E-3 | 2 | 339 | 2 | 6292 |