From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.741059922582] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
late endosome | 1.1672E-5 | 2 | 22 | 2 | 6292 |
endosome | 2.2085E-4 | 2 | 94 | 2 | 6292 |
Golgi apparatus | 7.3441E-4 | 2 | 171 | 2 | 6292 |
integral to membrane of membrane fraction | 9.5344E-4 | 2 | 3 | 1 | 6292 |
vacuolar proton-transporting V-type ATPase, V0 domain | 2.224E-3 | 2 | 7 | 1 | 6292 |
proton-transporting V-type ATPase, V0 domain | 2.224E-3 | 2 | 7 | 1 | 6292 |
trans-Golgi network | 4.1283E-3 | 2 | 13 | 1 | 6292 |
vacuolar proton-transporting V-type ATPase complex | 4.7627E-3 | 2 | 15 | 1 | 6292 |
proton-transporting V-type ATPase complex | 4.7627E-3 | 2 | 15 | 1 | 6292 |
proton-transporting two-sector ATPase complex, proton-transporting domain | 6.0308E-3 | 2 | 19 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
actin cortical patch localization | 3.1786E-4 | 2 | 1 | 1 | 6292 |
phospholipid translocation | 2.224E-3 | 2 | 7 | 1 | 6292 |
lipid translocation | 2.224E-3 | 2 | 7 | 1 | 6292 |
phospholipid transport | 3.811E-3 | 2 | 12 | 1 | 6292 |
vacuolar acidification | 7.6148E-3 | 2 | 24 | 1 | 6292 |
pH reduction | 7.6148E-3 | 2 | 24 | 1 | 6292 |
intracellular pH reduction | 7.6148E-3 | 2 | 24 | 1 | 6292 |
regulation of cellular pH | 7.9314E-3 | 2 | 25 | 1 | 6292 |
regulation of intracellular pH | 7.9314E-3 | 2 | 25 | 1 | 6292 |
G1 phase of mitotic cell cycle | 8.5646E-3 | 2 | 27 | 1 | 6292 |
G1 phase | 8.5646E-3 | 2 | 27 | 1 | 6292 |
regulation of pH | 9.1975E-3 | 2 | 29 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
ATPase activity, coupled to movement of substances | 8.6451E-5 | 2 | 59 | 2 | 6292 |
ATPase activity, coupled | 5.5711E-4 | 2 | 149 | 2 | 6292 |
ATPase activity | 1.1194E-3 | 2 | 211 | 2 | 6292 |
nucleoside-triphosphatase activity | 2.7262E-3 | 2 | 329 | 2 | 6292 |
substrate-specific transporter activity | 2.8436E-3 | 2 | 336 | 2 | 6292 |
phospholipid-translocating ATPase activity | 2.859E-3 | 2 | 9 | 1 | 6292 |
hydrolase activity, acting on acid anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
pyrophosphatase activity | 3.1391E-3 | 2 | 353 | 2 | 6292 |
transporter activity | 4.1132E-3 | 2 | 404 | 2 | 6292 |
proton-transporting ATPase activity, rotational mechanism | 4.1283E-3 | 2 | 13 | 1 | 6292 |
phospholipid transporter activity | 4.4455E-3 | 2 | 14 | 1 | 6292 |
cation-transporting ATPase activity | 5.0798E-3 | 2 | 16 | 1 | 6292 |
lipid transporter activity | 6.0308E-3 | 2 | 19 | 1 | 6292 |
ATPase activity, coupled to transmembrane movement of ions | 9.1975E-3 | 2 | 29 | 1 | 6292 |