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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.741059922582]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

late endosome 1.1672E-5 2 22 2 6292
endosome 2.2085E-4 2 94 2 6292
Golgi apparatus 7.3441E-4 2 171 2 6292
integral to membrane of membrane fraction 9.5344E-4 2 3 1 6292
vacuolar proton-transporting V-type ATPase, V0 domain 2.224E-3 2 7 1 6292
proton-transporting V-type ATPase, V0 domain 2.224E-3 2 7 1 6292
trans-Golgi network 4.1283E-3 2 13 1 6292
vacuolar proton-transporting V-type ATPase complex 4.7627E-3 2 15 1 6292
proton-transporting V-type ATPase complex 4.7627E-3 2 15 1 6292
proton-transporting two-sector ATPase complex, proton-transporting domain 6.0308E-3 2 19 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

actin cortical patch localization 3.1786E-4 2 1 1 6292
phospholipid translocation 2.224E-3 2 7 1 6292
lipid translocation 2.224E-3 2 7 1 6292
phospholipid transport 3.811E-3 2 12 1 6292
vacuolar acidification 7.6148E-3 2 24 1 6292
pH reduction 7.6148E-3 2 24 1 6292
intracellular pH reduction 7.6148E-3 2 24 1 6292
regulation of cellular pH 7.9314E-3 2 25 1 6292
regulation of intracellular pH 7.9314E-3 2 25 1 6292
G1 phase of mitotic cell cycle 8.5646E-3 2 27 1 6292
G1 phase 8.5646E-3 2 27 1 6292
regulation of pH 9.1975E-3 2 29 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ATPase activity, coupled to movement of substances 8.6451E-5 2 59 2 6292
ATPase activity, coupled 5.5711E-4 2 149 2 6292
ATPase activity 1.1194E-3 2 211 2 6292
nucleoside-triphosphatase activity 2.7262E-3 2 329 2 6292
substrate-specific transporter activity 2.8436E-3 2 336 2 6292
phospholipid-translocating ATPase activity 2.859E-3 2 9 1 6292
hydrolase activity, acting on acid anhydrides 3.1391E-3 2 353 2 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.1391E-3 2 353 2 6292
pyrophosphatase activity 3.1391E-3 2 353 2 6292
transporter activity 4.1132E-3 2 404 2 6292
proton-transporting ATPase activity, rotational mechanism 4.1283E-3 2 13 1 6292
phospholipid transporter activity 4.4455E-3 2 14 1 6292
cation-transporting ATPase activity 5.0798E-3 2 16 1 6292
lipid transporter activity 6.0308E-3 2 19 1 6292
ATPase activity, coupled to transmembrane movement of ions 9.1975E-3 2 29 1 6292

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