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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.859298757701]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
MEX67
  • cytoplasm
  • nuclear pore
    		•
  • mRNA export from nucleus
    		•
  • RNA binding
  • protein binding
  • structural constituent of nuclear pore
    		•
    NUP60
  • nuclear pore
    		•
  • nucleocytoplasmic transport
  • telomere maintenance
  • protein import into nucleus, docking
    		•
  • structural constituent of nuclear pore
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    pore complex 6.6999E-5 2 52 2 6292
    nuclear pore 6.6999E-5 2 52 2 6292
    nuclear envelope 9.9543E-4 2 199 2 6292
    integral to membrane 1.6363E-3 2 255 2 6292
    intrinsic to membrane 1.7276E-3 2 262 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292
    envelope 6.43E-3 2 505 2 6292
    organelle envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear transport 4.2367E-4 2 130 2 6292
    nucleocytoplasmic transport 4.2367E-4 2 130 2 6292
    protein import into nucleus, docking 1.2712E-3 2 4 1 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    structural constituent of nuclear pore 3.0316E-7 2 4 2 6292
    structural molecule activity 2.8947E-3 2 339 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle