From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.891043903622] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
GUT2 |
|
|
|
SDH1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitochondrial membrane part | 2.5011E-4 | 2 | 100 | 2 | 6292 |
respiratory chain complex II | 1.2712E-3 | 2 | 4 | 1 | 6292 |
mitochondrial respiratory chain complex II | 1.2712E-3 | 2 | 4 | 1 | 6292 |
succinate dehydrogenase complex (ubiquinone) | 1.2712E-3 | 2 | 4 | 1 | 6292 |
fumarate reductase complex | 1.2712E-3 | 2 | 4 | 1 | 6292 |
succinate dehydrogenase complex | 1.2712E-3 | 2 | 4 | 1 | 6292 |
mitochondrial membrane | 1.7808E-3 | 2 | 266 | 2 | 6292 |
mitochondrial envelope | 2.4514E-3 | 2 | 312 | 2 | 6292 |
integral to mitochondrial outer membrane | 4.1283E-3 | 2 | 13 | 1 | 6292 |
intrinsic to mitochondrial outer membrane | 4.1283E-3 | 2 | 13 | 1 | 6292 |
integral to mitochondrial membrane | 4.4455E-3 | 2 | 14 | 1 | 6292 |
mitochondrial part | 5.6881E-3 | 2 | 475 | 2 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
mitochondrial respiratory chain | 8.248E-3 | 2 | 26 | 1 | 6292 |
respiratory chain | 8.248E-3 | 2 | 26 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
coenzyme metabolic process | 3.6076E-4 | 2 | 120 | 2 | 6292 |
cofactor metabolic process | 5.9526E-4 | 2 | 154 | 2 | 6292 |
mitochondrial electron transport, succinate to ubiquinone | 1.2712E-3 | 2 | 4 | 1 | 6292 |
NADH oxidation | 3.811E-3 | 2 | 12 | 1 | 6292 |
acetyl-CoA catabolic process | 4.7627E-3 | 2 | 15 | 1 | 6292 |
NADH metabolic process | 4.7627E-3 | 2 | 15 | 1 | 6292 |
tricarboxylic acid cycle | 4.7627E-3 | 2 | 15 | 1 | 6292 |
acetyl-CoA metabolic process | 6.3477E-3 | 2 | 20 | 1 | 6292 |
coenzyme catabolic process | 6.3477E-3 | 2 | 20 | 1 | 6292 |
cofactor catabolic process | 6.9813E-3 | 2 | 22 | 1 | 6292 |
respiratory electron transport chain | 7.9314E-3 | 2 | 25 | 1 | 6292 |
electron transport chain | 7.9314E-3 | 2 | 25 | 1 | 6292 |
ATP synthesis coupled electron transport | 7.9314E-3 | 2 | 25 | 1 | 6292 |
mitochondrial ATP synthesis coupled electron transport | 7.9314E-3 | 2 | 25 | 1 | 6292 |
NAD metabolic process | 7.9314E-3 | 2 | 25 | 1 | 6292 |
oxidation reduction | 8.248E-3 | 2 | 26 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
glycerol-3-phosphate dehydrogenase activity | 3.1786E-4 | 2 | 1 | 1 | 6292 |
oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor | 1.5888E-3 | 2 | 5 | 1 | 6292 |
succinate dehydrogenase (ubiquinone) activity | 1.5888E-3 | 2 | 5 | 1 | 6292 |
succinate dehydrogenase activity | 1.5888E-3 | 2 | 5 | 1 | 6292 |
oxidoreductase activity | 1.9877E-3 | 2 | 281 | 2 | 6292 |
oxidoreductase activity, acting on the CH-CH group of donors | 7.6148E-3 | 2 | 24 | 1 | 6292 |