From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.18273910008] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
HMG1 |
|
|
|
HMG2 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
endoplasmic reticulum membrane | 4.4352E-4 | 2 | 133 | 2 | 6292 |
endoplasmic reticulum part | 5.6464E-4 | 2 | 150 | 2 | 6292 |
subsynaptic reticulum | 5.6464E-4 | 2 | 150 | 2 | 6292 |
mitochondrial matrix | 7.7811E-4 | 2 | 176 | 2 | 6292 |
mitochondrial lumen | 7.7811E-4 | 2 | 176 | 2 | 6292 |
nuclear envelope | 9.9543E-4 | 2 | 199 | 2 | 6292 |
nuclear membrane-endoplasmic reticulum network | 1.3539E-3 | 2 | 232 | 2 | 6292 |
endoplasmic reticulum | 3.3381E-3 | 2 | 364 | 2 | 6292 |
endomembrane system | 3.9918E-3 | 2 | 398 | 2 | 6292 |
mitochondrial part | 5.6881E-3 | 2 | 475 | 2 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
phytosteroid metabolic process | 1.6421E-5 | 2 | 26 | 2 | 6292 |
phytosteroid biosynthetic process | 1.6421E-5 | 2 | 26 | 2 | 6292 |
ergosterol biosynthetic process | 1.6421E-5 | 2 | 26 | 2 | 6292 |
ergosterol metabolic process | 1.6421E-5 | 2 | 26 | 2 | 6292 |
steroid biosynthetic process | 2.5061E-5 | 2 | 32 | 2 | 6292 |
sterol biosynthetic process | 2.5061E-5 | 2 | 32 | 2 | 6292 |
sterol metabolic process | 4.3504E-5 | 2 | 42 | 2 | 6292 |
steroid metabolic process | 4.5626E-5 | 2 | 43 | 2 | 6292 |
lipid biosynthetic process | 4.2367E-4 | 2 | 130 | 2 | 6292 |
alcohol metabolic process | 1.2172E-3 | 2 | 220 | 2 | 6292 |
lipid metabolic process | 1.4491E-3 | 2 | 240 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
hydroxymethylglutaryl-CoA reductase (NADPH) activity | 5.0527E-8 | 2 | 2 | 2 | 6292 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 1.3278E-4 | 2 | 73 | 2 | 6292 |
oxidoreductase activity, acting on CH-OH group of donors | 1.6371E-4 | 2 | 81 | 2 | 6292 |
oxidoreductase activity | 1.9877E-3 | 2 | 281 | 2 | 6292 |