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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.42047718736]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

spliceosomal complex 5.0022E-5 2 45 2 6292
U2-type spliceosomal complex 3.811E-3 2 12 1 6292
commitment complex 3.811E-3 2 12 1 6292
U1 snRNP 5.3968E-3 2 17 1 6292
ribonucleoprotein complex 6.6615E-3 2 514 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nuclear mRNA splicing, via spliceosome 2.4511E-4 2 99 2 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 2.5011E-4 2 100 2 6292
RNA splicing, via transesterification reactions 2.8654E-4 2 107 2 6292
nuclear mRNA 5'-splice site recognition 3.1786E-4 2 1 1 6292
RNA splicing 4.3685E-4 2 132 2 6292
mRNA processing 6.1087E-4 2 156 2 6292
nuclear mRNA cis splicing, via spliceosome 9.5344E-4 2 3 1 6292
mRNA metabolic process 1.1408E-3 2 213 2 6292
mRNA splice site selection 1.9064E-3 2 6 1 6292
RNA processing 3.6384E-3 2 380 2 6292
spliceosome assembly 5.7138E-3 2 18 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

pre-mRNA 5'-splice site binding 3.1786E-4 2 1 1 6292
first spliceosomal transesterification activity 1.9064E-3 2 6 1 6292
RNA binding 3.3934E-3 2 367 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle