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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Pbs2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 5 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitochondrial pyruvate dehydrogenase complex 4.7604E-3 5 6 1 6292
pyruvate dehydrogenase complex 4.7604E-3 5 6 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulation of kinase activity 6.2313E-7 5 26 3 6292
regulation of protein kinase activity 6.2313E-7 5 26 3 6292
regulation of transferase activity 6.2313E-7 5 26 3 6292
regulation of phosphorylation 1.076E-6 5 31 3 6292
regulation of phosphate metabolic process 2.016E-6 5 38 3 6292
regulation of phosphorus metabolic process 2.016E-6 5 38 3 6292
regulation of catalytic activity 3.1605E-6 5 44 3 6292
regulation of molecular function 3.1605E-6 5 44 3 6292
regulation of MAP kinase activity 7.5694E-6 5 6 2 6292
negative regulation of protein kinase activity 7.5694E-6 5 6 2 6292
negative regulation of kinase activity 7.5694E-6 5 6 2 6292
negative regulation of transferase activity 7.5694E-6 5 6 2 6292
regulation of signal transduction 1.4121E-5 5 8 2 6292
regulation of signaling process 1.4121E-5 5 8 2 6292
response to osmotic stress 1.7318E-5 5 77 3 6292
negative regulation of catalytic activity 1.8149E-5 5 9 2 6292
negative regulation of molecular function 1.8149E-5 5 9 2 6292
hyperosmotic response 2.2679E-5 5 10 2 6292
MAPKKK cascade involved in osmosensory signaling pathway 3.9273E-5 5 13 2 6292
regulation of cell communication 4.5804E-5 5 14 2 6292
response to abiotic stimulus 6.0995E-5 5 117 3 6292
osmosensory signaling pathway 1.0547E-4 5 21 2 6292
MAPKKK cascade 1.0547E-4 5 21 2 6292
cellular response to abiotic stimulus 1.1598E-4 5 22 2 6292
cellular response to osmotic stress 1.1598E-4 5 22 2 6292
intracellular protein kinase cascade 1.3848E-4 5 24 2 6292
signal transmission via phosphorylation event 1.3848E-4 5 24 2 6292
regulation of signaling pathway 1.8942E-4 5 28 2 6292
phosphorylation 2.1711E-4 5 179 3 6292
phosphorus metabolic process 4.5074E-4 5 229 3 6292
phosphate metabolic process 4.5074E-4 5 229 3 6292
cell communication 5.8536E-4 5 49 2 6292
activation of MAPK activity 7.9466E-4 5 1 1 6292
nuclear translocation of MAPK 7.9466E-4 5 1 1 6292
positive regulation of MAP kinase activity 7.9466E-4 5 1 1 6292
nuclear translocation of MAPK involved in osmosensory signaling pathway 7.9466E-4 5 1 1 6292
activation of MAPK activity involved in osmosensory signaling pathway 7.9466E-4 5 1 1 6292
protein import into nucleus, translocation 2.3825E-3 5 3 1 6292
intracellular signal transduction 3.1946E-3 5 115 2 6292
inactivation of MAPK activity 3.9682E-3 5 5 1 6292
negative regulation of MAP kinase activity 3.9682E-3 5 5 1 6292
inactivation of MAPK activity involved in osmosensory signaling pathway 3.9682E-3 5 5 1 6292
monocarboxylic acid metabolic process 4.3164E-3 5 134 2 6292
response to stress 4.3416E-3 5 497 3 6292
biotin metabolic process 4.7604E-3 5 6 1 6292
amide biosynthetic process 4.7604E-3 5 6 1 6292
biotin biosynthetic process 4.7604E-3 5 6 1 6292
intracellular signaling pathway 4.9713E-3 5 144 2 6292
regulation of cellular metabolic process 5.3949E-3 5 536 3 6292
regulation of metabolic process 5.7186E-3 5 547 3 6292
positive regulation of protein kinase activity 6.3431E-3 5 8 1 6292
positive regulation of kinase activity 6.3431E-3 5 8 1 6292
positive regulation of transferase activity 6.3431E-3 5 8 1 6292
signaling pathway 8.025E-3 5 184 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

adenosylmethionine-8-amino-7-oxononanoate transaminase activity 7.9466E-4 5 1 1 6292
MAP-kinase scaffold activity 1.5888E-3 5 2 1 6292
protein complex scaffold 1.5888E-3 5 2 1 6292
receptor signaling complex scaffold activity 1.5888E-3 5 2 1 6292
pyruvate dehydrogenase (acetyl-transferring) activity 3.1756E-3 5 4 1 6292
pyruvate dehydrogenase activity 3.1756E-3 5 4 1 6292
MAP kinase kinase activity 3.1756E-3 5 4 1 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 3.9682E-3 5 5 1 6292
protein serine/threonine/tyrosine kinase activity 5.552E-3 5 7 1 6292

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