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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdc53. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

SCF ubiquitin ligase complex 5.2364E-3 3 11 1 6292
cullin-RING ubiquitin ligase complex 6.6614E-3 3 14 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

inactivation of MAPK activity 2.3825E-3 3 5 1 6292
negative regulation of MAP kinase activity 2.3825E-3 3 5 1 6292
inactivation of MAPK activity involved in osmosensory signaling pathway 2.3825E-3 3 5 1 6292
regulation of MAP kinase activity 2.8585E-3 3 6 1 6292
negative regulation of protein kinase activity 2.8585E-3 3 6 1 6292
negative regulation of kinase activity 2.8585E-3 3 6 1 6292
negative regulation of transferase activity 2.8585E-3 3 6 1 6292
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 3.3344E-3 3 7 1 6292
regulation of signal transduction 3.8101E-3 3 8 1 6292
regulation of signaling process 3.8101E-3 3 8 1 6292
negative regulation of catalytic activity 4.2857E-3 3 9 1 6292
negative regulation of molecular function 4.2857E-3 3 9 1 6292
protein ubiquitination during ubiquitin-dependent protein catabolic process 5.2364E-3 3 11 1 6292
MAPKKK cascade involved in osmosensory signaling pathway 6.1865E-3 3 13 1 6292
regulation of cell communication 6.6614E-3 3 14 1 6292
tRNA splicing, via endonucleolytic cleavage and ligation 7.6106E-3 3 16 1 6292
RNA splicing, via endonucleolytic cleavage and ligation 7.6106E-3 3 16 1 6292
post-translational protein modification 9.2699E-3 3 357 2 6292
osmosensory signaling pathway 9.9809E-3 3 21 1 6292
MAPKKK cascade 9.9809E-3 3 21 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication origin binding 6.1865E-3 3 13 1 6292
protein binding, bridging 9.5071E-3 3 20 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle