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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Pep3. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

extrinsic to vacuolar membrane 9.5344E-4 3 2 1 6292
HOPS complex 2.8585E-3 3 6 1 6292
extrinsic to organelle membrane 5.7116E-3 3 12 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

cellular localization 1.0628E-3 3 643 3 6292
Golgi vesicle transport 2.089E-3 3 168 2 6292
inactivation of MAPK activity 2.3825E-3 3 5 1 6292
negative regulation of MAP kinase activity 2.3825E-3 3 5 1 6292
inactivation of MAPK activity involved in osmosensory signaling pathway 2.3825E-3 3 5 1 6292
regulation of MAP kinase activity 2.8585E-3 3 6 1 6292
negative regulation of protein kinase activity 2.8585E-3 3 6 1 6292
negative regulation of kinase activity 2.8585E-3 3 6 1 6292
negative regulation of transferase activity 2.8585E-3 3 6 1 6292
regulation of signal transduction 3.8101E-3 3 8 1 6292
regulation of signaling process 3.8101E-3 3 8 1 6292
negative regulation of catalytic activity 4.2857E-3 3 9 1 6292
negative regulation of molecular function 4.2857E-3 3 9 1 6292
localization 4.7701E-3 3 1060 3 6292
Golgi to endosome transport 5.2364E-3 3 11 1 6292
vesicle docking during exocytosis 5.7116E-3 3 12 1 6292
anatomical structure homeostasis 5.9917E-3 3 286 2 6292
telomere organization 5.9917E-3 3 286 2 6292
telomere maintenance 5.9917E-3 3 286 2 6292
MAPKKK cascade involved in osmosensory signaling pathway 6.1865E-3 3 13 1 6292
membrane docking 6.6614E-3 3 14 1 6292
vesicle docking 6.6614E-3 3 14 1 6292
regulation of cell communication 6.6614E-3 3 14 1 6292
tRNA splicing, via endonucleolytic cleavage and ligation 7.6106E-3 3 16 1 6292
RNA splicing, via endonucleolytic cleavage and ligation 7.6106E-3 3 16 1 6292
vesicle-mediated transport 8.4226E-3 3 340 2 6292
osmosensory signaling pathway 9.9809E-3 3 21 1 6292
MAPKKK cascade 9.9809E-3 3 21 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ARF guanyl-nucleotide exchange factor activity 2.8585E-3 3 6 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle