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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ptc1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) 1.2712E-3 2 4 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

inactivation of MAPK activity 1.5888E-3 2 5 1 6292
negative regulation of MAP kinase activity 1.5888E-3 2 5 1 6292
inactivation of MAPK activity involved in osmosensory signaling pathway 1.5888E-3 2 5 1 6292
trehalose biosynthetic process 1.9064E-3 2 6 1 6292
glycoside biosynthetic process 1.9064E-3 2 6 1 6292
disaccharide biosynthetic process 1.9064E-3 2 6 1 6292
regulation of MAP kinase activity 1.9064E-3 2 6 1 6292
negative regulation of protein kinase activity 1.9064E-3 2 6 1 6292
negative regulation of kinase activity 1.9064E-3 2 6 1 6292
negative regulation of transferase activity 1.9064E-3 2 6 1 6292
regulation of signal transduction 2.5415E-3 2 8 1 6292
regulation of signaling process 2.5415E-3 2 8 1 6292
trehalose metabolic process 2.859E-3 2 9 1 6292
negative regulation of catalytic activity 2.859E-3 2 9 1 6292
negative regulation of molecular function 2.859E-3 2 9 1 6292
glycoside metabolic process 3.1764E-3 2 10 1 6292
MAPKKK cascade involved in osmosensory signaling pathway 4.1283E-3 2 13 1 6292
disaccharide metabolic process 4.1283E-3 2 13 1 6292
regulation of cell communication 4.4455E-3 2 14 1 6292
oligosaccharide biosynthetic process 5.0798E-3 2 16 1 6292
tRNA splicing, via endonucleolytic cleavage and ligation 5.0798E-3 2 16 1 6292
RNA splicing, via endonucleolytic cleavage and ligation 5.0798E-3 2 16 1 6292
response to stress 6.2277E-3 2 497 2 6292
osmosensory signaling pathway 6.6645E-3 2 21 1 6292
MAPKKK cascade 6.6645E-3 2 21 1 6292
cellular response to abiotic stimulus 6.9813E-3 2 22 1 6292
cellular response to osmotic stress 6.9813E-3 2 22 1 6292
intracellular protein kinase cascade 7.6148E-3 2 24 1 6292
signal transmission via phosphorylation event 7.6148E-3 2 24 1 6292
regulation of kinase activity 8.248E-3 2 26 1 6292
regulation of protein kinase activity 8.248E-3 2 26 1 6292
regulation of transferase activity 8.248E-3 2 26 1 6292
oligosaccharide metabolic process 8.8811E-3 2 28 1 6292
regulation of signaling pathway 8.8811E-3 2 28 1 6292
protein amino acid dephosphorylation 8.8811E-3 2 28 1 6292
mitochondrion distribution 9.1975E-3 2 29 1 6292
mitochondrion inheritance 9.1975E-3 2 29 1 6292
mitochondrion localization 9.5139E-3 2 30 1 6292
regulation of phosphorylation 9.8303E-3 2 31 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

phosphatase activity 1.8902E-4 2 87 2 6292
phosphoric ester hydrolase activity 2.6026E-4 2 102 2 6292
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 9.5344E-4 2 3 1 6292
trehalose-phosphatase activity 9.5344E-4 2 3 1 6292
carbohydrate phosphatase activity 2.224E-3 2 7 1 6292
hydrolase activity, acting on ester bonds 2.929E-3 2 341 2 6292
UDP-glucosyltransferase activity 4.4455E-3 2 14 1 6292
glucosyltransferase activity 5.0798E-3 2 16 1 6292
protein serine/threonine phosphatase activity 8.248E-3 2 26 1 6292
UDP-glycosyltransferase activity 8.5646E-3 2 27 1 6292

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