YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rad16. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
GND1
  • cytoplasm
  • mitochondrion
  • response to oxidative stress
  • pentose-phosphate shunt, oxidative branch
  • phosphogluconate dehydrogenase (decarboxylating) activity
  • HHF1, HHF2
  • nucleus
  • nucleoplasm part
  • nuclear nucleosome
  • chromosome
  • replication fork protection complex
  • chromatin remodeling complex
  • nucleosome
  • histone acetyltransferase complex
  • nucleoplasm
  • histone H3-K79 methylation
  • DNA repair
  • negative regulation of transcription
  • chromatin assembly or disassembly
  • positive regulation of transcription
  • nucleosome assembly
  • DNA binding
  • HTB2
  • nuclear nucleosome
  • chromatin assembly or disassembly
  • DNA binding
  • HTZ1
  • chromatin assembly complex
  • nuclear chromatin
  • chromatin silencing at silent mating-type cassette
  • regulation of transcription from RNA polymerase II promoter
  • chromatin binding
  • RAD16
  • repairosome
  • nucleotide-excision repair factor 4 complex
  • nucleotide-excision repair, DNA damage recognition
  • DNA-dependent ATPase activity
  • damaged DNA binding
  • RAD7
  • repairosome
  • nucleotide-excision repair factor 4 complex
  • nucleotide-excision repair, DNA damage recognition
  • DNA-dependent ATPase activity
  • damaged DNA binding
  • SHP1
  • nucleus
  • cytoplasm
  • ascospore formation
  • proteasomal ubiquitin-dependent protein catabolic process
  • glycogen metabolic process
  • telomere maintenance
  • protein phosphatase type 1 regulator activity
  • TMA29
  • nucleus
  • cytoplasm
  • ribosome
  • metabolic process
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
  • TSA2
  • cytoplasm
  • response to oxidative stress
  • thioredoxin peroxidase activity
  • peroxiredoxin activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleotide-excision repair factor 4 complex 1.0898E-5 9 4 2 6292
    repairosome 1.0898E-5 9 4 2 6292
    nuclear nucleosome 1.1916E-4 9 12 2 6292
    nucleosome 1.1916E-4 9 12 2 6292
    nuclear chromatin 1.1973E-4 9 73 3 6292
    chromatin 1.4042E-4 9 77 3 6292
    nucleotide-excision repair complex 3.7663E-4 9 21 2 6292
    nuclear chromosome part 1.9904E-3 9 190 3 6292
    protein-DNA complex 2.7869E-3 9 57 2 6292
    replication fork protection complex 2.859E-3 9 2 1 6292
    nuclear chromosome 3.3545E-3 9 228 3 6292
    chromosomal part 3.7449E-3 9 237 3 6292
    chromosome 5.6423E-3 9 274 3 6292
    nucleus 6.9589E-3 9 2041 7 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleotide-excision repair, DNA damage recognition 3.8057E-5 9 7 2 6292
    response to stress 2.9062E-4 9 497 5 6292
    chromosome organization 4.8941E-4 9 555 5 6292
    chromatin assembly or disassembly 1.0561E-3 9 35 2 6292
    nucleotide-excision repair 1.245E-3 9 38 2 6292
    histone H3-K79 methylation 1.4304E-3 9 1 1 6292
    DNA repair 2.0512E-3 9 192 3 6292
    response to stimulus 2.1816E-3 9 766 5 6292
    histone lysine methylation 2.859E-3 9 2 1 6292
    response to DNA damage stimulus 3.7002E-3 9 236 3 6292
    response to oxidative stress 4.0601E-3 9 69 2 6292
    DNA metabolic process 6.3704E-3 9 585 4 6292
    cellular response to stress 6.6158E-3 9 290 3 6292
    pentose-phosphate shunt, oxidative branch 8.5551E-3 9 6 1 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.7168E-3 9 1566 6 6292
    glucose metabolic process 9.888E-3 9 109 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    damaged DNA binding 9.9377E-5 9 11 2 6292
    DNA binding 2.8694E-4 9 256 4 6292
    DNA-dependent ATPase activity 2.5969E-3 9 55 2 6292
    phosphogluconate dehydrogenase (decarboxylating) activity 2.859E-3 9 2 1 6292
    oxidoreductase activity 6.0565E-3 9 281 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle