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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdc11. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC10
  • cellular bud neck septin ring
  • axial cellular bud site selection
  • bipolar cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • cell morphogenesis involved in conjugation with cellular fusion
  • ascospore wall assembly
  • GTPase activity
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC11
  • cellular bud neck septin ring
  • prospore membrane
  • ascospore wall
  • mating projection base
  • axial cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC12
  • cellular bud neck septin ring
  • cytoplasm
  • axial cellular bud site selection
  • bipolar cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • GTPase activity
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC3
  • cellular bud neck septin ring
  • prospore membrane
  • ascospore wall
  • mating projection base
  • axial cellular bud site selection
  • cell morphogenesis
  • cellular cell wall organization
  • cytokinesis
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CLU1
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • mitochondrion organization
  • molecular_function
  • RPN1
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • cytoplasm
  • endoplasmic reticulum
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • protein binding, bridging
  • TOP2
  • nucleus
  • mitochondrion
  • synaptonemal complex
  • reciprocal meiotic recombination
  • DNA strand elongation involved in DNA replication
  • regulation of mitotic recombination
  • chromatin assembly or disassembly
  • DNA topological change
  • DNA topoisomerase (ATP-hydrolyzing) activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular bud neck septin ring 6.7465E-11 7 9 4 6292
    cleavage apparatus septin structure 6.7465E-11 7 9 4 6292
    cellular bud neck septin structure 6.7465E-11 7 9 4 6292
    septin cytoskeleton 7.292E-10 7 15 4 6292
    septin ring 7.292E-10 7 15 4 6292
    cell division site part 9.3325E-9 7 27 4 6292
    cell division site 9.3325E-9 7 27 4 6292
    cell cortex part 1.7203E-6 7 96 4 6292
    cell cortex 2.8665E-6 7 109 4 6292
    cellular bud neck 5.6289E-6 7 129 4 6292
    cellular bud 1.5376E-5 7 166 4 6292
    site of polarized growth 1.6125E-5 7 168 4 6292
    mating projection base 2.2223E-5 7 7 2 6292
    cytoskeletal part 3.2812E-5 7 201 4 6292
    cytoskeleton 4.3594E-5 7 216 4 6292
    spore wall 4.7546E-5 7 10 2 6292
    ascospore wall 4.7546E-5 7 10 2 6292
    prospore membrane 1.7981E-4 7 19 2 6292
    intracellular immature spore 1.7981E-4 7 19 2 6292
    ascospore-type prospore 1.7981E-4 7 19 2 6292
    cell projection part 8.9439E-4 7 42 2 6292
    cell projection 1.2171E-3 7 49 2 6292
    mating projection 1.2171E-3 7 49 2 6292
    non-membrane-bounded organelle 1.3072E-3 7 959 5 6292
    intracellular non-membrane-bounded organelle 1.3072E-3 7 959 5 6292
    cytoplasmic part 1.4786E-3 7 2482 7 6292
    fungal-type cell wall 5.4848E-3 7 105 2 6292
    synaptonemal complex 5.552E-3 7 5 1 6292
    cell wall 5.5873E-3 7 106 2 6292
    external encapsulating structure 5.5873E-3 7 106 2 6292
    eukaryotic translation initiation factor 3 complex 7.7654E-3 7 7 1 6292
    proteasome regulatory particle, base subcomplex 9.9746E-3 7 9 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    axial cellular bud site selection 1.262E-8 7 29 4 6292
    cellular bud site selection 6.0093E-7 7 74 4 6292
    cytokinesis, site selection 6.0093E-7 7 74 4 6292
    cell cycle cytokinesis 8.2409E-7 7 80 4 6292
    establishment of cell polarity 1.0038E-6 7 84 4 6292
    establishment or maintenance of cell polarity 1.053E-6 7 85 4 6292
    cell budding 1.3263E-6 7 90 4 6292
    asexual reproduction 1.3263E-6 7 90 4 6292
    cytokinetic process 1.4492E-6 7 92 4 6292
    cytokinesis 3.1965E-6 7 112 4 6292
    cell morphogenesis 4.9627E-6 7 125 4 6292
    cellular component morphogenesis 7.369E-6 7 138 4 6292
    cell division 8.9766E-6 7 145 4 6292
    cell wall organization 1.8115E-5 7 173 4 6292
    external encapsulating structure organization 1.8115E-5 7 173 4 6292
    cellular cell wall organization 1.8115E-5 7 173 4 6292
    cell wall organization or biogenesis 3.7562E-5 7 208 4 6292
    cellular cell wall organization or biogenesis 3.7562E-5 7 208 4 6292
    reproduction of a single-celled organism 4.4395E-5 7 217 4 6292
    cell cycle process 5.1689E-5 7 490 5 6292
    cell cycle 7.236E-5 7 525 5 6292
    anatomical structure morphogenesis 8.6358E-5 7 257 4 6292
    anatomical structure development 9.0379E-5 7 260 4 6292
    cellular developmental process 1.142E-4 7 276 4 6292
    reproduction 2.2392E-4 7 328 4 6292
    developmental process 2.3199E-4 7 331 4 6292
    conjugation with cellular fusion 2.5277E-4 7 125 3 6292
    conjugation 2.5881E-4 7 126 3 6292
    multi-organism process 3.7631E-4 7 143 3 6292
    bipolar cellular bud site selection 5.8524E-4 7 34 2 6292
    cellular component organization 1.3786E-3 7 1582 6 6292
    sexual reproduction 1.571E-3 7 233 3 6292
    regulation of mitotic recombination 5.552E-3 7 5 1 6292
    DNA topological change 8.8705E-3 7 8 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphatidylinositol binding 1.124E-10 7 10 4 6292
    phosphoinositide binding 3.4986E-8 7 37 4 6292
    phospholipid binding 6.5224E-8 7 43 4 6292
    lipid binding 1.2139E-7 7 50 4 6292
    structural constituent of cytoskeleton 1.5417E-7 7 53 4 6292
    structural molecule activity 2.5455E-4 7 339 4 6292
    binding 4.326E-4 7 1294 6 6292
    DNA topoisomerase (ATP-hydrolyzing) activity 1.1125E-3 7 1 1 6292
    GTPase activity 1.8819E-3 7 61 2 6292
    DNA topoisomerase activity 6.6592E-3 7 6 1 6292

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