From Publication: | Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3. |
Notes: | This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rpc40. The topolgies of protein complexes in this experiment are unknown. |
Complex Size: | 35 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
RNA polymerase complex | 1.3882E-20 | 35 | 31 | 12 | 6292 |
DNA-directed RNA polymerase complex | 1.3882E-20 | 35 | 31 | 12 | 6292 |
nuclear DNA-directed RNA polymerase complex | 1.3882E-20 | 35 | 31 | 12 | 6292 |
DNA-directed RNA polymerase III complex | 3.9338E-17 | 35 | 17 | 9 | 6292 |
DNA-directed RNA polymerase I complex | 2.9086E-13 | 35 | 14 | 7 | 6292 |
nucleolar part | 3.4067E-9 | 35 | 45 | 7 | 6292 |
membrane-enclosed lumen | 2.4663E-7 | 35 | 700 | 16 | 6292 |
nuclear lumen | 4.0075E-7 | 35 | 453 | 13 | 6292 |
organelle lumen | 7.6452E-7 | 35 | 660 | 15 | 6292 |
intracellular organelle lumen | 7.6452E-7 | 35 | 660 | 15 | 6292 |
nucleoplasm | 1.0339E-6 | 35 | 264 | 10 | 6292 |
nucleoplasm part | 5.1637E-6 | 35 | 245 | 9 | 6292 |
protein complex | 3.5223E-5 | 35 | 1137 | 17 | 6292 |
nucleolus | 1.3038E-4 | 35 | 211 | 7 | 6292 |
DNA-directed RNA polymerase II, core complex | 1.916E-3 | 35 | 12 | 2 | 6292 |
macromolecular complex | 3.3177E-3 | 35 | 1635 | 17 | 6292 |
nuclear part | 4.4973E-3 | 35 | 1103 | 13 | 6292 |
intracellular organelle part | 9.3065E-3 | 35 | 2282 | 20 | 6292 |
organelle part | 9.3065E-3 | 35 | 2282 | 20 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
RNA polymerase activity | 5.3394E-20 | 35 | 34 | 12 | 6292 |
DNA-directed RNA polymerase activity | 5.3394E-20 | 35 | 34 | 12 | 6292 |
nucleotidyltransferase activity | 4.3435E-11 | 35 | 168 | 12 | 6292 |
ligase activity, forming carbon-carbon bonds | 6.2849E-7 | 35 | 4 | 3 | 6292 |
transferase activity, transferring phosphorus-containing groups | 1.3635E-6 | 35 | 420 | 12 | 6292 |
catalytic activity | 1.3808E-6 | 35 | 2150 | 26 | 6292 |
pyruvate carboxylase activity | 3.0063E-5 | 35 | 2 | 2 | 6292 |
transferase activity | 1.9818E-4 | 35 | 797 | 13 | 6292 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 6.6527E-4 | 35 | 73 | 4 | 6292 |
oxidoreductase activity, acting on CH-OH group of donors | 9.8536E-4 | 35 | 81 | 4 | 6292 |
biotin carboxylase activity | 5.5626E-3 | 35 | 1 | 1 | 6292 |
glutamine-fructose-6-phosphate transaminase (isomerizing) activity | 5.5626E-3 | 35 | 1 | 1 | 6292 |
acetyl-CoA hydrolase activity | 5.5626E-3 | 35 | 1 | 1 | 6292 |
ligase activity | 9.1482E-3 | 35 | 150 | 4 | 6292 |