From Publication: | Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3. |
Notes: | This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ess1. The topolgies of protein complexes in this experiment are unknown. |
Complex Size: | 17 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear lumen | 9.8647E-5 | 17 | 453 | 7 | 6292 |
DNA-directed RNA polymerase II, holoenzyme | 4.1574E-4 | 17 | 56 | 3 | 6292 |
DNA-directed RNA polymerase II, core complex | 4.4637E-4 | 17 | 12 | 2 | 6292 |
nucleoplasm | 5.1126E-4 | 17 | 264 | 5 | 6292 |
organelle lumen | 1.0252E-3 | 17 | 660 | 7 | 6292 |
intracellular organelle lumen | 1.0252E-3 | 17 | 660 | 7 | 6292 |
nucleus | 1.4135E-3 | 17 | 2041 | 12 | 6292 |
membrane-enclosed lumen | 1.4596E-3 | 17 | 700 | 7 | 6292 |
DNA-directed RNA polymerase complex | 3.0514E-3 | 17 | 31 | 2 | 6292 |
RNA polymerase complex | 3.0514E-3 | 17 | 31 | 2 | 6292 |
nuclear DNA-directed RNA polymerase complex | 3.0514E-3 | 17 | 31 | 2 | 6292 |
nucleoplasm part | 3.5752E-3 | 17 | 245 | 4 | 6292 |
DSIF complex | 5.3968E-3 | 17 | 2 | 1 | 6292 |
proteasome complex | 7.2051E-3 | 17 | 48 | 2 | 6292 |
transcription factor TFIIF complex | 8.0849E-3 | 17 | 3 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
cellular macromolecule metabolic process | 8.7181E-4 | 17 | 2285 | 13 | 6292 |
macromolecule metabolic process | 1.1807E-3 | 17 | 2349 | 13 | 6292 |
transcription from RNA polymerase II promoter | 1.5101E-3 | 17 | 335 | 5 | 6292 |
primary metabolic process | 2.4078E-3 | 17 | 2896 | 14 | 6292 |
'de novo' posttranslational protein folding | 2.7018E-3 | 17 | 1 | 1 | 6292 |
chaperone mediated protein folding requiring cofactor | 2.7018E-3 | 17 | 1 | 1 | 6292 |
chaperone-mediated protein folding | 2.7018E-3 | 17 | 1 | 1 | 6292 |
cellular metabolic process | 4.1361E-3 | 17 | 3033 | 14 | 6292 |
arginine catabolic process | 5.3968E-3 | 17 | 2 | 1 | 6292 |
metabolic process | 6.562E-3 | 17 | 3157 | 14 | 6292 |
RNA metabolic process | 8.6957E-3 | 17 | 954 | 7 | 6292 |
transcription, DNA-dependent | 8.8228E-3 | 17 | 503 | 5 | 6292 |
RNA biosynthetic process | 9.1953E-3 | 17 | 508 | 5 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
cis-trans isomerase activity | 6.135E-4 | 17 | 14 | 2 | 6292 |
peptidyl-prolyl cis-trans isomerase activity | 6.135E-4 | 17 | 14 | 2 | 6292 |
transcription elongation regulator activity | 1.1437E-3 | 17 | 19 | 2 | 6292 |
cAMP-dependent protein kinase inhibitor activity | 2.7018E-3 | 17 | 1 | 1 | 6292 |
ornithine-oxo-acid transaminase activity | 2.7018E-3 | 17 | 1 | 1 | 6292 |
RNA polymerase activity | 3.6639E-3 | 17 | 34 | 2 | 6292 |
DNA-directed RNA polymerase activity | 3.6639E-3 | 17 | 34 | 2 | 6292 |
endopeptidase activity | 9.0541E-3 | 17 | 54 | 2 | 6292 |
catalytic activity | 9.7716E-3 | 17 | 2150 | 11 | 6292 |