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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CSL4
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • response to exogenous dsRNA
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • DIS3
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • mitochondrion
  • nuclear outer membrane
  • mRNA catabolic process
  • polyadenylation-dependent ncRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • LRP1
  • nuclear exosome (RNase complex)
  • DNA repair
  • snRNA processing
  • double-strand break repair via homologous recombination
  • telomere maintenance
  • snoRNA processing
  • double-strand break repair via nonhomologous end joining
  • mRNA catabolic process
  • processing of 27S pre-rRNA
  • molecular_function
  • MTR3
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP4
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RNA binding
  • RRP40
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • ribosome assembly
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RNA binding
  • RRP42
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP43
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP45
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP46
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP6
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • ribosome biogenesis
  • mRNA catabolic process
  • polyadenylation-dependent ncRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • SKI2
  • cytoplasm
  • nucleolus
  • regulation of translation
  • response to exogenous dsRNA
  • mRNA catabolic process
  • RNA helicase activity
  • translation repressor activity
  • SKI3
  • nucleus
  • cytoplasm
  • response to exogenous dsRNA
  • mRNA catabolic process
  • translation repressor activity
  • SKI6
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • response to exogenous dsRNA
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • SKI7
  • cytoplasm
  • exosome (RNase complex)
  • response to exogenous dsRNA
  • mRNA catabolic process
  • protein binding
  • SRP1
  • nucleus
  • cytoplasm
  • nucleocytoplasmic transport
  • protein transmembrane transporter activity
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • YIR035C
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    exosome (RNase complex) 2.9553E-32 21 16 13 6292
    nuclear exosome (RNase complex) 1.6748E-29 21 15 12 6292
    cytoplasmic exosome (RNase complex) 8.721E-25 21 12 10 6292
    nuclear outer membrane 4.2261E-20 21 86 13 6292
    nuclear membrane 2.2335E-19 21 97 13 6292
    outer membrane 8.0237E-16 21 178 13 6292
    organelle outer membrane 8.0237E-16 21 178 13 6292
    nuclear envelope 3.4991E-15 21 199 13 6292
    nuclear membrane-endoplasmic reticulum network 2.6178E-14 21 232 13 6292
    endomembrane system 2.7453E-11 21 398 13 6292
    envelope 5.5286E-10 21 505 13 6292
    organelle envelope 5.5286E-10 21 505 13 6292
    nuclear part 6.0814E-9 21 1103 16 6292
    membrane part 1.5823E-8 21 662 13 6292
    organelle membrane 2.7211E-8 21 692 13 6292
    macromolecular complex 2.0726E-7 21 1635 17 6292
    nucleus 6.7057E-7 21 2041 18 6292
    protein complex 9.8924E-6 21 1137 13 6292
    membrane 1.7965E-5 21 1198 13 6292
    small nucleolar ribonucleoprotein complex 8.1439E-5 21 72 4 6292
    organelle part 2.2313E-4 21 2282 16 6292
    intracellular organelle part 2.2313E-4 21 2282 16 6292
    membrane-bounded organelle 2.3032E-3 21 3771 19 6292
    intracellular membrane-bounded organelle 2.3032E-3 21 3771 19 6292
    cytoplasm 4.5379E-3 21 3552 18 6292
    nucleolus 4.695E-3 21 211 4 6292
    intracellular part 6.1098E-3 21 4938 21 6292
    intracellular 7.149E-3 21 4975 21 6292
    intracellular organelle 7.9071E-3 21 4070 19 6292
    organelle 7.938E-3 21 4071 19 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA catabolic process 4.0627E-26 21 69 15 6292
    RNA catabolic process 4.7087E-25 21 80 15 6292
    mRNA metabolic process 2.445E-18 21 213 15 6292
    cellular macromolecule catabolic process 6.8259E-17 21 265 15 6292
    macromolecule catabolic process 3.2849E-16 21 294 15 6292
    RNA metabolic process 3.6101E-14 21 954 19 6292
    cellular catabolic process 5.7411E-14 21 415 15 6292
    catabolic process 8.0377E-13 21 496 15 6292
    response to exogenous dsRNA 5.1862E-12 21 7 5 6292
    response to dsRNA 5.1862E-12 21 7 5 6292
    nucleic acid metabolic process 5.7872E-11 21 1415 19 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.7905E-10 21 1566 19 6292
    cellular nitrogen compound metabolic process 3.6218E-9 21 1770 19 6292
    nitrogen compound metabolic process 4.4976E-9 21 1791 19 6292
    cellular macromolecule metabolic process 3.7885E-7 21 2285 19 6292
    macromolecule metabolic process 6.2289E-7 21 2349 19 6292
    primary metabolic process 2.5653E-5 21 2896 19 6292
    maturation of SSU-rRNA 3.7059E-5 21 59 4 6292
    cellular metabolic process 5.7449E-5 21 3033 19 6292
    response to organic substance 6.991E-5 21 137 5 6292
    metabolic process 1.1494E-4 21 3157 19 6292
    polyadenylation-dependent RNA catabolic process 2.9353E-4 21 8 2 6292
    polyadenylation-dependent ncRNA catabolic process 2.9353E-4 21 8 2 6292
    ncRNA processing 5.7814E-4 21 215 5 6292
    ribosome biogenesis 7.098E-4 21 346 6 6292
    rRNA processing 7.4771E-4 21 128 4 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.0949E-4 21 13 2 6292
    rRNA metabolic process 9.6524E-4 21 137 4 6292
    ribonucleoprotein complex biogenesis 1.0705E-3 21 374 6 6292
    ncRNA metabolic process 1.2986E-3 21 257 5 6292
    cellular process 6.0383E-3 21 4426 20 6292
    RNA processing 7.1184E-3 21 380 5 6292
    response to chemical stimulus 7.277E-3 21 382 5 6292
    ncRNA 5'-end processing 9.9809E-3 21 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.9809E-3 21 3 1 6292
    rRNA 5'-end processing 9.9809E-3 21 3 1 6292
    RNA 5'-end processing 9.9809E-3 21 3 1 6292
    snRNA processing 9.9809E-3 21 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.9809E-3 21 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    3'-5'-exoribonuclease activity 3.0838E-23 21 23 11 6292
    exoribonuclease activity, producing 5'-phosphomonoesters 1.7545E-22 21 26 11 6292
    exoribonuclease activity 1.7545E-22 21 26 11 6292
    exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6.4211E-21 21 34 11 6292
    3'-5' exonuclease activity 9.3503E-21 21 35 11 6292
    exonuclease activity 2.9419E-19 21 46 11 6292
    ribonuclease activity 2.6123E-13 21 149 11 6292
    nuclease activity 6.4408E-12 21 199 11 6292
    hydrolase activity, acting on ester bonds 2.1873E-9 21 341 11 6292
    hydrolase activity 7.4517E-7 21 911 13 6292
    translation repressor activity 3.1768E-5 21 3 2 6292
    snoRNA binding 1.3566E-4 21 31 3 6292
    translation regulator activity 5.731E-4 21 11 2 6292
    RNA binding 6.1472E-3 21 367 5 6292
    RNA helicase activity 8.4298E-3 21 42 2 6292
    catalytic activity 8.5084E-3 21 2150 13 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle