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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BDF2
  • nucleus
  • biological_process
  • molecular_function
  • CDC55
  • nucleus
  • cellular bud tip
  • cellular bud neck
  • protein phosphatase type 2A complex
  • mitotic cell cycle spindle assembly checkpoint
  • negative regulation of exit from mitosis
  • protein amino acid dephosphorylation
  • pseudohyphal growth
  • actin filament organization
  • budding cell bud growth
  • translation
  • protein serine/threonine phosphatase activity
  • protein phosphatase type 2A regulator activity
  • CKB1
  • protein kinase CK2 complex
  • G2/M transition of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • flocculation via cell wall protein-carbohydrate interaction
  • protein amino acid phosphorylation
  • response to DNA damage stimulus
  • regulation of transcription from RNA polymerase III promoter
  • regulation of transcription from RNA polymerase I promoter
  • cellular ion homeostasis
  • protein kinase CK2 regulator activity
  • DYN1
  • cytoplasmic dynein complex
  • cytoplasmic microtubule
  • mitotic spindle elongation
  • establishment of mitotic spindle orientation
  • mitotic sister chromatid segregation
  • nuclear migration along microtubule
  • motor activity
  • ECM5
  • nucleus
  • cellular cell wall organization
  • molecular_function
  • GLY1
  • cytosol
  • glycine biosynthetic process
  • threonine catabolic process
  • threonine aldolase activity
  • HAT1
  • nucleus
  • cytoplasm
  • histone acetyltransferase complex
  • histone acetylation
  • chromatin silencing at telomere
  • histone binding
  • HAT2
  • nucleus
  • cytoplasm
  • histone acetyltransferase complex
  • chromatin assembly or disassembly
  • histone acetylation
  • chromatin silencing at telomere
  • histone binding
  • HHF1, HHF2
  • nucleus
  • nucleoplasm part
  • nuclear nucleosome
  • chromosome
  • replication fork protection complex
  • chromatin remodeling complex
  • nucleosome
  • histone acetyltransferase complex
  • nucleoplasm
  • histone H3-K79 methylation
  • DNA repair
  • negative regulation of transcription
  • chromatin assembly or disassembly
  • positive regulation of transcription
  • nucleosome assembly
  • DNA binding
  • HIF1
  • nucleus
  • histone acetyltransferase complex
  • histone acetylation
  • chromatin silencing at telomere
  • nucleosome assembly
  • histone binding
  • HSM3
  • cytoplasm
  • mismatch repair
  • molecular_function
  • ICL1
  • cellular_component
  • glyoxylate cycle
  • isocitrate lyase activity
  • IML1
  • fungal-type vacuole membrane
  • biological_process
  • molecular_function
  • KAP123
  • nucleus
  • cytoplasm
  • nuclear pore
  • protein import into nucleus
  • protein transmembrane transporter activity
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • LIP2
  • mitochondrion
  • protein lipoylation
  • ligase activity
  • MAC1
  • nucleus
  • response to drug
  • regulation of protein catabolic process
  • positive regulation of transcription from RNA polymerase II promoter
  • cellular cadmium ion homeostasis
  • specific RNA polymerase II transcription factor activity
  • MDN1
  • nucleus
  • mitochondrion
  • nucleoplasm
  • protein complex assembly
  • rRNA processing
  • ribosomal large subunit assembly
  • ATPase activity
  • MIS1
  • mitochondrion
  • ribosome biogenesis
  • folic acid biosynthetic process
  • anaerobic purine catabolic process
  • nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
  • acetate biosynthetic process from carbon monoxide
  • formate-tetrahydrofolate ligase activity
  • methenyltetrahydrofolate cyclohydrolase activity
  • methylenetetrahydrofolate dehydrogenase (NADP+) activity
  • MSB1
  • cellular bud tip
  • cellular bud neck
  • mitochondrion
  • cell division
  • regulation of transport
  • establishment of cell polarity
  • regulation of signal transduction
  • reproduction
  • molecular_function
  • NIP1
  • multi-eIF complex
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • ribosome biogenesis
  • translational initiation
  • translation initiation factor activity
  • NMD5
  • nucleus
  • cytoplasm
  • protein import into nucleus
  • protein transmembrane transporter activity
  • PFK1
  • 6-phosphofructokinase complex
  • cytoplasm
  • mitochondrion
  • glycolysis
  • 6-phosphofructokinase activity
  • PRO1
  • cytoplasm
  • telomere maintenance
  • ribosome biogenesis
  • proline biosynthetic process
  • glutamate 5-kinase activity
  • PRT1
  • multi-eIF complex
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • translation initiation factor activity
  • PSD2
  • fungal-type vacuole membrane
  • Golgi membrane
  • phosphatidylcholine biosynthetic process
  • phosphatidylserine decarboxylase activity
  • PSE1
  • nucleus
  • cytoplasm
  • mRNA export from nucleus
  • protein import into nucleus
  • protein transmembrane transporter activity
  • PSH1
  • nucleus
  • RNA elongation from RNA polymerase II promoter
  • molecular_function
  • RPA135
  • DNA-directed RNA polymerase I complex
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
  • DNA-directed RNA polymerase activity
  • RPC40
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
  • DNA-directed RNA polymerase activity
  • RPG1
  • incipient cellular bud site
  • cytoplasm
  • ribosome
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • translation initiation factor activity
  • RPN12
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RPN3
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • molecular_function
  • RPN6
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • structural molecule activity
  • RPN8
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • molecular_function
  • RPN9
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • structural molecule activity
  • RPT2
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT3
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT5
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT6
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RSC3
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • regulation of transcription, DNA-dependent
  • DNA binding
  • DNA-dependent ATPase activity
  • SAM1
  • cytoplasm
  • methionine metabolic process
  • methionine adenosyltransferase activity
  • TEL1
  • nucleus
  • mitochondrion
  • DNA double-strand break processing
  • telomere maintenance
  • telomere maintenance via telomerase
  • phosphorylation
  • response to DNA damage stimulus
  • protein kinase activity
  • TSC11
  • TORC2 complex
  • regulation of cell growth
  • cellular cell wall organization
  • establishment or maintenance of actin cytoskeleton polarity
  • sphingolipid biosynthetic process
  • protein binding
  • USO1
  • soluble fraction
  • ER to Golgi vesicle-mediated transport
  • protein complex assembly
  • molecular_function
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • VTH2
  • cellular_component
  • Golgi to vacuole transport
  • signal sequence binding
  • YFR006W
  • cytoplasm
  • biological_process
  • X-Pro aminopeptidase activity
  • YPR077C

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    proteasome accessory complex 3.6577E-14 49 23 9 6292
    proteasome regulatory particle 3.6577E-14 49 23 9 6292
    proteasome complex 6.5001E-11 49 48 9 6292
    proteasome regulatory particle, lid subcomplex 5.6879E-9 49 10 5 6292
    protein complex 1.5318E-7 49 1137 25 6292
    proteasome regulatory particle, base subcomplex 3.9761E-7 49 9 4 6292
    eukaryotic translation initiation factor 3 complex 1.5202E-5 49 7 3 6292
    macromolecular complex 4.5824E-5 49 1635 26 6292
    histone acetyltransferase complex 3.5057E-4 49 44 4 6292
    multi-eIF complex 1.6147E-3 49 8 2 6292
    DNA-directed RNA polymerase I complex 5.0935E-3 49 14 2 6292
    nuclear lumen 7.4057E-3 49 453 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein catabolic process 1.3984E-6 49 189 10 6292
    modification-dependent protein catabolic process 2.4719E-6 49 156 9 6292
    ubiquitin-dependent protein catabolic process 2.4719E-6 49 156 9 6292
    proteolysis involved in cellular protein catabolic process 2.8964E-6 49 159 9 6292
    modification-dependent macromolecule catabolic process 3.7442E-6 49 164 9 6292
    cellular protein catabolic process 5.2853E-6 49 171 9 6292
    macromolecule catabolic process 1.1413E-5 49 294 11 6292
    proteolysis 1.1457E-5 49 188 9 6292
    catabolic process 1.5258E-5 49 496 14 6292
    cellular macromolecule catabolic process 2.8405E-5 49 265 10 6292
    cellular catabolic process 5.684E-5 49 415 12 6292
    primary metabolic process 8.4836E-5 49 2896 36 6292
    protein metabolic process 1.5816E-4 49 1136 20 6292
    cellular protein metabolic process 2.3798E-4 49 1074 19 6292
    cellular process 2.5998E-4 49 4426 45 6292
    cellular metabolic process 2.7418E-4 49 3033 36 6292
    metabolic process 7.3133E-4 49 3157 36 6292
    cellular macromolecule metabolic process 8.9706E-4 49 2285 29 6292
    macromolecule metabolic process 1.49E-3 49 2349 29 6292
    transcription from RNA polymerase I promoter 1.5546E-3 49 30 3 6292
    chromatin assembly or disassembly 2.4386E-3 49 35 3 6292
    histone acetylation 2.6458E-3 49 36 3 6292
    translational initiation 4.1171E-3 49 42 3 6292
    covalent chromatin modification 4.6864E-3 49 88 4 6292
    histone modification 4.6864E-3 49 88 4 6292
    ribosome biogenesis 4.7939E-3 49 346 8 6292
    protein amino acid acetylation 5.3267E-3 49 46 3 6292
    protein import into nucleus 6.0036E-3 49 48 3 6292
    protein localization in nucleus 6.0036E-3 49 48 3 6292
    nuclear import 6.0036E-3 49 48 3 6292
    nucleosome assembly 6.6504E-3 49 16 2 6292
    ribonucleoprotein complex biogenesis 7.616E-3 49 374 8 6292
    cellular cadmium ion homeostasis 7.7877E-3 49 1 1 6292
    cellular transition metal ion homeostasis 7.7877E-3 49 1 1 6292
    pteridine and derivative biosynthetic process 7.7877E-3 49 1 1 6292
    nitrogenous compound catabolic process 7.7877E-3 49 1 1 6292
    anaerobic purine catabolic process 7.7877E-3 49 1 1 6292
    acetate biosynthetic process from carbon monoxide 7.7877E-3 49 1 1 6292
    histone H3-K79 methylation 7.7877E-3 49 1 1 6292
    protein lipoylation 7.7877E-3 49 1 1 6292
    cadmium ion homeostasis 7.7877E-3 49 1 1 6292
    transition metal ion homeostasis 7.7877E-3 49 1 1 6292
    folic acid biosynthetic process 7.7877E-3 49 1 1 6292
    chromatin silencing at telomere 8.7666E-3 49 55 3 6292
    transcription 8.8947E-3 49 552 10 6292
    chromatin assembly 9.337E-3 49 19 2 6292
    chromatin modification 9.442E-3 49 168 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    macromolecule transmembrane transporter activity 3.6085E-5 49 9 3 6292
    protein transmembrane transporter activity 3.6085E-5 49 9 3 6292
    endopeptidase activity 5.5197E-5 49 54 5 6292
    histone binding 1.5214E-4 49 14 3 6292
    peptidase activity, acting on L-amino acid peptides 7.9619E-4 49 95 5 6292
    translation initiation factor activity 1.1385E-3 49 27 3 6292
    carbon-carbon lyase activity 1.5546E-3 49 30 3 6292
    translation factor activity, nucleic acid binding 4.6982E-3 49 44 3 6292
    ATPase activity 5.5565E-3 49 211 6 6292
    threonine aldolase activity 7.7877E-3 49 1 1 6292
    glutamate 5-kinase activity 7.7877E-3 49 1 1 6292
    isocitrate lyase activity 7.7877E-3 49 1 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle