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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CMD1
  • incipient cellular bud site
  • cellular bud tip
  • central plaque of spindle pole body
  • cytoplasm
  • cellular bud neck
  • mating projection tip
  • cytoskeleton organization
  • cell budding
  • vacuole fusion, non-autophagic
  • mitosis
  • endocytosis
  • protein binding
  • calcium ion binding
  • calcium-dependent protein binding
  • CSL4
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • response to exogenous dsRNA
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • CTR9
  • nucleus
  • transcription elongation factor complex
  • Cdc73/Paf1 complex
  • histone methylation
  • transcription from RNA polymerase II promoter
  • chromosome segregation
  • RNA elongation from RNA polymerase II promoter
  • RNA polymerase II transcription elongation factor activity
  • triplex DNA binding
  • DIS3
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • mitochondrion
  • nuclear outer membrane
  • mRNA catabolic process
  • polyadenylation-dependent ncRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • GCN1
  • mitochondrion
  • cytosol
  • regulation of translational elongation
  • molecular_function
  • MAM33
  • mitochondrial matrix
  • mitochondrion
  • response to drug
  • aerobic respiration
  • molecular_function
  • MLC1
  • cellular bud tip
  • cellular bud neck
  • vesicle
  • cytokinesis, actomyosin contractile ring assembly
  • vesicle targeting
  • protein localization
  • cytokinesis
  • myosin II heavy chain binding
  • myosin V binding
  • MTR3
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • MYO2
  • incipient cellular bud site
  • cellular bud tip
  • cellular bud neck
  • fungal-type vacuole membrane
  • myosin V complex
  • mating projection tip
  • vesicle
  • filamentous actin
  • mitochondrion inheritance
  • vacuole inheritance
  • establishment of mitotic spindle orientation
  • unidimensional cell growth
  • vesicle-mediated transport
  • Golgi inheritance
  • vesicle transport along actin filament
  • peroxisome inheritance
  • membrane addition at site of cytokinesis
  • budding cell apical bud growth
  • actin filament binding
  • calmodulin binding
  • microfilament motor activity
  • NMD5
  • nucleus
  • cytoplasm
  • protein import into nucleus
  • protein transmembrane transporter activity
  • RRP4
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RNA binding
  • RRP40
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • ribosome assembly
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RNA binding
  • RRP42
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP43
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP45
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP46
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • RRP6
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • ribosome biogenesis
  • mRNA catabolic process
  • polyadenylation-dependent ncRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • SAM1
  • cytoplasm
  • methionine metabolic process
  • methionine adenosyltransferase activity
  • SHE4
  • cytoplasm
  • intracellular mRNA localization
  • actin cytoskeleton organization
  • gene conversion at mating-type locus
  • myosin binding
  • SKI6
  • cytoplasmic exosome (RNase complex)
  • nuclear exosome (RNase complex)
  • nuclear outer membrane
  • response to exogenous dsRNA
  • mRNA catabolic process
  • 3'-5'-exoribonuclease activity
  • SKI7
  • cytoplasm
  • exosome (RNase complex)
  • response to exogenous dsRNA
  • mRNA catabolic process
  • protein binding
  • SRP1
  • nucleus
  • cytoplasm
  • nucleocytoplasmic transport
  • protein transmembrane transporter activity
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    exosome (RNase complex) 6.1442E-28 24 16 12 6292
    nuclear exosome (RNase complex) 2.2253E-25 24 15 11 6292
    cytoplasmic exosome (RNase complex) 4.8451E-24 24 12 10 6292
    nuclear outer membrane 3.4827E-15 24 86 11 6292
    nuclear membrane 1.3864E-14 24 97 11 6292
    outer membrane 1.2383E-11 24 178 11 6292
    organelle outer membrane 1.2383E-11 24 178 11 6292
    nuclear envelope 4.1933E-11 24 199 11 6292
    nuclear membrane-endoplasmic reticulum network 2.2142E-10 24 232 11 6292
    endomembrane system 6.6819E-8 24 398 11 6292
    envelope 7.614E-7 24 505 11 6292
    organelle envelope 7.614E-7 24 505 11 6292
    organelle membrane 2.2064E-6 24 692 12 6292
    membrane part 1.1122E-5 24 662 11 6292
    protein complex 1.1786E-5 24 1137 14 6292
    macromolecular complex 3.2834E-5 24 1635 16 6292
    nuclear part 5.0758E-5 24 1103 13 6292
    membrane 5.9943E-4 24 1198 12 6292
    cytoplasm 1.2003E-3 24 3552 21 6292
    cellular bud tip 1.2466E-3 24 57 3 6292
    nucleus 2.346E-3 24 2041 15 6292
    intracellular organelle part 2.3613E-3 24 2282 16 6292
    organelle part 2.3613E-3 24 2282 16 6292
    cytoplasmic part 6.3246E-3 24 2482 16 6292
    myosin V complex 7.6148E-3 24 2 1 6292
    filamentous actin 7.6148E-3 24 2 1 6292
    unconventional myosin complex 7.6148E-3 24 2 1 6292
    mating projection tip 7.684E-3 24 35 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA catabolic process 2.7091E-18 24 69 12 6292
    RNA catabolic process 1.8156E-17 24 80 12 6292
    mRNA metabolic process 3.1504E-12 24 213 12 6292
    cellular macromolecule catabolic process 4.1967E-11 24 265 12 6292
    macromolecule catabolic process 1.4191E-10 24 294 12 6292
    cellular catabolic process 7.5891E-9 24 415 12 6292
    catabolic process 5.6855E-8 24 496 12 6292
    RNA metabolic process 1.5767E-7 24 954 15 6292
    response to exogenous dsRNA 1.6901E-6 24 7 3 6292
    response to dsRNA 1.6901E-6 24 7 3 6292
    nucleic acid metabolic process 4.5075E-6 24 1415 16 6292
    cellular nitrogen compound metabolic process 1.6727E-5 24 1770 17 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.8279E-5 24 1566 16 6292
    nitrogen compound metabolic process 1.9858E-5 24 1791 17 6292
    vesicle localization 8.3283E-5 24 4 2 6292
    cellular process 2.1149E-4 24 4426 24 6292
    polyadenylation-dependent RNA catabolic process 3.8504E-4 24 8 2 6292
    polyadenylation-dependent ncRNA catabolic process 3.8504E-4 24 8 2 6292
    cellular macromolecule metabolic process 6.0595E-4 24 2285 17 6292
    macromolecule metabolic process 8.7706E-4 24 2349 17 6292
    cellular metabolic process 1.8975E-3 24 3033 19 6292
    metabolic process 3.426E-3 24 3157 19 6292
    primary metabolic process 3.7669E-3 24 2896 18 6292
    Golgi inheritance 3.8144E-3 24 1 1 6292
    establishment of vesicle localization 7.6148E-3 24 2 1 6292
    developmental growth involved in morphogenesis 7.6148E-3 24 2 1 6292
    vesicle transport along actin filament 7.6148E-3 24 2 1 6292
    actin filament-based movement 7.6148E-3 24 2 1 6292
    developmental growth 7.6148E-3 24 2 1 6292
    unidimensional cell growth 7.6148E-3 24 2 1 6292
    membrane addition at site of cytokinesis 7.6148E-3 24 2 1 6292
    vesicle targeting 7.6148E-3 24 2 1 6292
    actin filament-based process 9.5406E-3 24 117 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    3'-5'-exoribonuclease activity 2.1709E-22 24 23 11 6292
    exoribonuclease activity, producing 5'-phosphomonoesters 1.2335E-21 24 26 11 6292
    exoribonuclease activity 1.2335E-21 24 26 11 6292
    exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4.4985E-20 24 34 11 6292
    3'-5' exonuclease activity 6.5478E-20 24 35 11 6292
    exonuclease activity 2.0502E-18 24 46 11 6292
    ribonuclease activity 1.7392E-12 24 149 11 6292
    nuclease activity 4.1933E-11 24 199 11 6292
    hydrolase activity, acting on ester bonds 1.3354E-8 24 341 11 6292
    hydrolase activity 5.9785E-6 24 911 13 6292
    myosin binding 1.3848E-4 24 5 2 6292
    macromolecule transmembrane transporter activity 4.939E-4 24 9 2 6292
    protein transmembrane transporter activity 4.939E-4 24 9 2 6292
    cytoskeletal protein binding 1.3781E-3 24 59 3 6292
    calmodulin binding 3.8144E-3 24 1 1 6292
    triplex DNA binding 3.8144E-3 24 1 1 6292
    myosin heavy chain binding 3.8144E-3 24 1 1 6292
    myosin II heavy chain binding 3.8144E-3 24 1 1 6292
    calcium-dependent protein binding 3.8144E-3 24 1 1 6292
    myosin V binding 3.8144E-3 24 1 1 6292
    binding 4.6729E-3 24 1294 11 6292
    protein binding 6.3048E-3 24 612 7 6292
    methionine adenosyltransferase activity 7.6148E-3 24 2 1 6292
    myosin II binding 7.6148E-3 24 2 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle