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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARP7
  • nucleus
  • SWI/SNF complex
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • general RNA polymerase II transcription factor activity
  • NPL6
  • nucleus
  • RSC complex
  • chromatin remodeling
  • protein import into nucleus
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • response to DNA damage stimulus
  • DNA-dependent ATPase activity
  • RSC1
  • RSC complex
  • ATP-dependent chromatin remodeling
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RSC2
  • RSC complex
  • sister chromatid cohesion
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RSC3
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • regulation of transcription, DNA-dependent
  • DNA binding
  • DNA-dependent ATPase activity
  • RSC4
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • RSC58
  • RSC complex
  • chromatin remodeling
  • molecular_function
  • RSC6
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • RSC8
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RSC9
  • RSC complex
  • chromatin remodeling
  • ATP-dependent chromatin remodeling
  • rRNA transcription
  • regulation of transcription from RNA polymerase II promoter
  • DNA-dependent ATPase activity
  • chromatin binding
  • SFH1
  • RSC complex
  • G2/M transition of mitotic cell cycle
  • ATP-dependent chromatin remodeling
  • chromosome segregation
  • chromatin remodeling at centromere
  • double-strand break repair
  • DNA-dependent ATPase activity
  • STH1
  • RSC complex
  • cytoskeleton organization
  • ATP-dependent chromatin remodeling
  • chromosome segregation
  • chromatin remodeling at centromere
  • meiosis
  • double-strand break repair
  • ATPase activity
  • DNA-dependent ATPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RSC complex 1.5838E-32 12 20 12 6292
    chromatin remodeling complex 1.1622E-22 12 99 12 6292
    nuclear part 8.0153E-10 12 1103 12 6292
    protein complex 1.1559E-9 12 1137 12 6292
    macromolecular complex 9.1989E-8 12 1635 12 6292
    nucleus 1.3278E-6 12 2041 12 6292
    organelle part 5.0851E-6 12 2282 12 6292
    intracellular organelle part 5.0851E-6 12 2282 12 6292
    membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    intracellular membrane-bounded organelle 2.1329E-3 12 3771 12 6292
    intracellular organelle 5.3355E-3 12 4070 12 6292
    organelle 5.3513E-3 12 4071 12 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ATP-dependent chromatin remodeling 6.088E-27 12 26 11 6292
    chromatin remodeling 9.1555E-25 12 68 12 6292
    chromatin modification 8.8748E-20 12 168 12 6292
    chromatin organization 9.2279E-19 12 203 12 6292
    chromosome organization 1.9889E-13 12 555 12 6292
    organelle organization 1.0391E-9 12 1127 12 6292
    double-strand break repair 3.8507E-8 12 57 5 6292
    cellular component organization 6.186E-8 12 1582 12 6292
    response to DNA damage stimulus 1.9985E-6 12 236 6 6292
    chromatin remodeling at centromere 3.3348E-6 12 2 2 6292
    cellular response to stress 6.6531E-6 12 290 6 6292
    double-strand break repair via nonhomologous end joining 1.1909E-5 12 25 3 6292
    DNA repair 1.6712E-5 12 192 5 6292
    non-recombinational repair 3.0686E-5 12 34 3 6292
    cellular response to stimulus 3.1107E-5 12 379 6 6292
    response to stress 1.4422E-4 12 497 6 6292
    DNA metabolic process 3.5676E-4 12 585 6 6292
    nucleic acid metabolic process 1.3186E-3 12 1415 8 6292
    response to stimulus 1.5399E-3 12 766 6 6292
    chromosome segregation 1.5818E-3 12 128 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.6723E-3 12 1566 8 6292
    rRNA transcription 5.7116E-3 12 3 1 6292
    cellular nitrogen compound metabolic process 6.1479E-3 12 1770 8 6292
    nitrogen compound metabolic process 6.653E-3 12 1791 8 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA-dependent ATPase activity 9.3883E-23 12 55 11 6292
    ATPase activity, coupled 1.0673E-17 12 149 11 6292
    ATPase activity 5.4377E-16 12 211 11 6292
    nucleoside-triphosphatase activity 7.7881E-14 12 329 11 6292
    hydrolase activity, acting on acid anhydrides 1.7031E-13 12 353 11 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1.7031E-13 12 353 11 6292
    pyrophosphatase activity 1.7031E-13 12 353 11 6292
    hydrolase activity 5.8014E-9 12 911 11 6292
    catalytic activity 6.0184E-5 12 2150 11 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle