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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase complex 1.1742E-15 6 23 6 6292
chromatin remodeling complex 1.3033E-11 6 99 6 6292
nucleoplasm part 3.2848E-9 6 245 6 6292
nucleoplasm 5.1651E-9 6 264 6 6292
nuclear lumen 1.3504E-7 6 453 6 6292
organelle lumen 1.3052E-6 6 660 6 6292
intracellular organelle lumen 1.3052E-6 6 660 6 6292
membrane-enclosed lumen 1.8602E-6 6 700 6 6292
nuclear part 2.8697E-5 6 1103 6 6292
protein complex 3.4445E-5 6 1137 6 6292
macromolecular complex 3.0579E-4 6 1635 6 6292
nucleus 1.1592E-3 6 2041 6 6292
organelle part 2.2664E-3 6 2282 6 6292
intracellular organelle part 2.2664E-3 6 2282 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of meiosis 4.0935E-15 6 8 5 6292
regulation of meiosis 1.9214E-12 6 22 5 6292
regulation of meiotic cell cycle 1.9214E-12 6 22 5 6292
histone deacetylation 5.8863E-12 6 27 5 6292
protein amino acid deacetylation 8.6566E-12 6 29 5 6292
negative regulation of cell cycle process 1.4673E-11 6 32 5 6292
regulation of cell cycle process 1.8548E-9 6 81 5 6292
covalent chromatin modification 2.8333E-9 6 88 5 6292
histone modification 2.8333E-9 6 88 5 6292
regulation of cell cycle 2.1399E-8 6 131 5 6292
meiosis 5.876E-8 6 160 5 6292
M phase of meiotic cell cycle 5.876E-8 6 160 5 6292
meiotic cell cycle 6.6549E-8 6 164 5 6292
chromatin modification 7.514E-8 6 168 5 6292
chromatin organization 1.9466E-7 6 203 5 6292
negative regulation of cellular process 5.5307E-7 6 250 5 6292
negative regulation of biological process 5.8711E-7 6 253 5 6292
M phase 1.244E-6 6 294 5 6292
post-translational protein modification 3.2755E-6 6 357 5 6292
cell cycle phase 4.2398E-6 6 376 5 6292
cell cycle process 1.5781E-5 6 490 5 6292
protein modification process 1.7269E-5 6 499 5 6292
cell cycle 2.2202E-5 6 525 5 6292
chromosome organization 2.9217E-5 6 555 5 6292
macromolecule modification 3.3042E-5 6 569 5 6292
protein metabolic process 3.4263E-5 6 1136 6 6292
regulation of cellular process 1.7215E-4 6 796 5 6292
regulation of biological process 2.0387E-4 6 824 5 6292
cellular protein metabolic process 7.4048E-4 6 1074 5 6292
organelle organization 9.3483E-4 6 1127 5 6292
biological regulation 1.333E-3 6 1213 5 6292
macromolecule metabolic process 2.6967E-3 6 2349 6 6292
cellular component organization 4.7462E-3 6 1582 5 6292
primary metabolic process 9.4808E-3 6 2896 6 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

NAD-independent histone deacetylase activity 1.5353E-15 6 7 5 6292
NAD-dependent protein deacetylase activity 9.2092E-15 6 9 5 6292
NAD-dependent histone deacetylase activity 9.2092E-15 6 9 5 6292
histone deacetylase activity 1.4673E-11 6 32 5 6292
protein deacetylase activity 1.4673E-11 6 32 5 6292
deacetylase activity 2.3645E-11 6 35 5 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1.245E-10 6 48 5 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.7405E-9 6 80 5 6292
hydrolase activity 3.3278E-4 6 911 5 6292
catalytic activity 1.5845E-3 6 2150 6 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle