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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 6 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CDC10
  • cellular bud neck septin ring
  • axial cellular bud site selection
  • bipolar cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • cell morphogenesis involved in conjugation with cellular fusion
  • ascospore wall assembly
  • GTPase activity
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC11
  • cellular bud neck septin ring
  • prospore membrane
  • ascospore wall
  • mating projection base
  • axial cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC12
  • cellular bud neck septin ring
  • cytoplasm
  • axial cellular bud site selection
  • bipolar cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • GTPase activity
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC3
  • cellular bud neck septin ring
  • prospore membrane
  • ascospore wall
  • mating projection base
  • axial cellular bud site selection
  • cell morphogenesis
  • cellular cell wall organization
  • cytokinesis
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC37
  • cytoplasm
  • MAPKKK cascade involved in osmosensory signaling pathway
  • regulation of stress-activated MAPK cascade
  • spindle pole body duplication in nuclear envelope
  • unfolded protein binding
  • SHS1
  • septin ring
  • cell morphogenesis
  • cytokinesis
  • structural constituent of cytoskeleton
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    septin ring 2.1931E-13 6 15 5 6292
    septin cytoskeleton 2.1931E-13 6 15 5 6292
    cellular bud neck septin structure 2.8932E-11 6 9 4 6292
    cellular bud neck septin ring 2.8932E-11 6 9 4 6292
    cleavage apparatus septin structure 2.8932E-11 6 9 4 6292
    cell division site 4.0114E-9 6 27 4 6292
    cell division site part 4.0114E-9 6 27 4 6292
    cell cortex part 4.4159E-9 6 96 5 6292
    cell cortex 8.4256E-9 6 109 5 6292
    cytoskeletal part 1.8522E-7 6 201 5 6292
    cytoskeleton 2.6583E-7 6 216 5 6292
    cellular bud neck 2.4513E-6 6 129 4 6292
    cellular bud 6.7281E-6 6 166 4 6292
    site of polarized growth 7.0577E-6 6 168 4 6292
    mating projection base 1.5882E-5 6 7 2 6292
    spore wall 3.399E-5 6 10 2 6292
    ascospore wall 3.399E-5 6 10 2 6292
    prospore membrane 1.2867E-4 6 19 2 6292
    intracellular immature spore 1.2867E-4 6 19 2 6292
    ascospore-type prospore 1.2867E-4 6 19 2 6292
    non-membrane-bounded organelle 4.2731E-4 6 959 5 6292
    intracellular non-membrane-bounded organelle 4.2731E-4 6 959 5 6292
    cell projection part 6.4156E-4 6 42 2 6292
    cell projection 8.7368E-4 6 49 2 6292
    mating projection 8.7368E-4 6 49 2 6292
    fungal-type cell wall 3.9607E-3 6 105 2 6292
    cell wall 4.0352E-3 6 106 2 6292
    external encapsulating structure 4.0352E-3 6 106 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    axial cellular bud site selection 5.426E-9 6 29 4 6292
    cytokinesis 9.6712E-9 6 112 5 6292
    cell morphogenesis 1.6878E-8 6 125 5 6292
    cellular component morphogenesis 2.7845E-8 6 138 5 6292
    cell division 3.5755E-8 6 145 5 6292
    cellular bud site selection 2.5985E-7 6 74 4 6292
    cytokinesis, site selection 2.5985E-7 6 74 4 6292
    cell cycle cytokinesis 3.5663E-7 6 80 4 6292
    establishment of cell polarity 4.3463E-7 6 84 4 6292
    establishment or maintenance of cell polarity 4.5598E-7 6 85 4 6292
    cell budding 5.7469E-7 6 90 4 6292
    asexual reproduction 5.7469E-7 6 90 4 6292
    cytokinetic process 6.2811E-7 6 92 4 6292
    anatomical structure morphogenesis 6.3506E-7 6 257 5 6292
    anatomical structure development 6.7302E-7 6 260 5 6292
    cellular developmental process 9.0727E-7 6 276 5 6292
    developmental process 2.2474E-6 6 331 5 6292
    cell wall organization 7.9341E-6 6 173 4 6292
    external encapsulating structure organization 7.9341E-6 6 173 4 6292
    cellular cell wall organization 7.9341E-6 6 173 4 6292
    cell cycle process 1.5781E-5 6 490 5 6292
    cell wall organization or biogenesis 1.6526E-5 6 208 4 6292
    cellular cell wall organization or biogenesis 1.6526E-5 6 208 4 6292
    reproduction of a single-celled organism 1.9555E-5 6 217 4 6292
    cell cycle 2.2202E-5 6 525 5 6292
    reproduction 1.0008E-4 6 328 4 6292
    conjugation with cellular fusion 1.4656E-4 6 125 3 6292
    conjugation 1.5008E-4 6 126 3 6292
    multi-organism process 2.1868E-4 6 143 3 6292
    cellular component organization 2.5085E-4 6 1582 6 6292
    bipolar cellular bud site selection 4.1945E-4 6 34 2 6292
    sexual reproduction 9.229E-4 6 233 3 6292
    stress-activated MAPK cascade 9.5359E-4 6 1 1 6292
    regulation of MAPKKK cascade 9.5359E-4 6 1 1 6292
    regulation of intracellular protein kinase cascade 9.5359E-4 6 1 1 6292
    regulation of stress-activated MAPK cascade 9.5359E-4 6 1 1 6292
    regulation of stress-activated protein kinase signaling pathway 9.5359E-4 6 1 1 6292
    stress-activated protein kinase signaling pathway 9.5359E-4 6 1 1 6292
    regulation of cellular response to stress 1.9064E-3 6 2 1 6292
    regulation of response to stress 2.8585E-3 6 3 1 6292
    regulation of response to stimulus 9.5019E-3 6 10 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphatidylinositol binding 4.8208E-11 6 10 4 6292
    structural constituent of cytoskeleton 2.0852E-10 6 53 5 6292
    phosphoinositide binding 1.5057E-8 6 37 4 6292
    phospholipid binding 2.8093E-8 6 43 4 6292
    lipid binding 5.2331E-8 6 50 4 6292
    structural molecule activity 2.5314E-6 6 339 5 6292
    GTPase activity 1.3526E-3 6 61 2 6292
    binding 1.819E-3 6 1294 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle