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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 14 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
GIN4
  • cellular bud neck
  • axial cellular bud site selection
  • septin ring assembly
  • protein amino acid phosphorylation
  • budding cell bud growth
  • septin checkpoint
  • protein kinase activity
  • HFD1
  • lipid particle
  • integral to mitochondrial outer membrane
  • endosome
  • mitochondrion
  • mitochondrial outer membrane
  • cellular aldehyde metabolic process
  • 3-chloroallyl aldehyde dehydrogenase activity
  • HTZ1
  • chromatin assembly complex
  • nuclear chromatin
  • chromatin silencing at silent mating-type cassette
  • regulation of transcription from RNA polymerase II promoter
  • chromatin binding
  • KAP114
  • nucleus
  • cytoplasm
  • protein import into nucleus
  • protein transmembrane transporter activity
  • KCC4
  • cellular bud neck
  • axial cellular bud site selection
  • septin ring assembly
  • protein amino acid phosphorylation
  • budding cell bud growth
  • septin checkpoint
  • protein kinase activity
  • NAP1
  • nucleus
  • cytoplasm
  • nuclear nucleosome
  • M phase of mitotic cell cycle
  • budding cell bud growth
  • nucleosome assembly
  • histone binding
  • PRO3
  • cytoplasm
  • proline biosynthetic process
  • pyrroline-5-carboxylate reductase activity
  • REI1
  • cytoplasm
  • nucleocytoplasmic transport
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • budding cell bud growth
  • mitotic cell cycle
  • molecular_function
  • RIM11
  • cytoplasm
  • ascospore formation
  • proteolysis
  • protein amino acid phosphorylation
  • response to stress
  • protein serine/threonine kinase activity
  • glycogen synthase kinase 3 activity
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • UBC8
  • cytoplasm
  • protein polyubiquitination
  • negative regulation of gluconeogenesis
  • protein monoubiquitination
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
  • ubiquitin-protein ligase activity
  • VIP1
  • cytoplasm
  • actin cytoskeleton organization
  • molecular_function
  • WTM1
  • nucleus
  • regulation of meiosis
  • transcription corepressor activity
  • YKR011C
  • nucleus
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    budding cell bud growth 6.8484E-7 14 34 4 6292
    cell budding 3.5125E-5 14 90 4 6292
    asexual reproduction 3.5125E-5 14 90 4 6292
    cytokinesis checkpoint 6.8619E-5 14 6 2 6292
    regulation of cytokinesis 6.8619E-5 14 6 2 6292
    septin checkpoint 6.8619E-5 14 6 2 6292
    reproduction of a single-celled organism 7.2321E-5 14 217 5 6292
    septin ring organization 9.5944E-5 14 7 2 6292
    regulation of cell division 9.5944E-5 14 7 2 6292
    septin cytoskeleton organization 9.5944E-5 14 7 2 6292
    septin ring assembly 9.5944E-5 14 7 2 6292
    cell division 2.2629E-4 14 145 4 6292
    growth 2.2629E-4 14 145 4 6292
    reproduction 5.059E-4 14 328 5 6292
    protein amino acid phosphorylation 1.3601E-3 14 103 3 6292
    axial cellular bud site selection 1.8037E-3 14 29 2 6292
    regulation of cell cycle 2.7139E-3 14 131 3 6292
    cell cycle 4.2068E-3 14 525 5 6292
    cellular protein complex assembly 6.1587E-3 14 54 2 6292
    post-translational protein modification 6.4746E-3 14 357 4 6292
    phosphorylation 6.5393E-3 14 179 3 6292
    proline biosynthetic process 6.6614E-3 14 3 1 6292
    cellular macromolecular complex assembly 6.8483E-3 14 182 3 6292
    cell cycle checkpoint 7.0781E-3 14 58 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    pyrroline-5-carboxylate reductase activity 2.225E-3 14 1 1 6292
    protein kinase activity 4.4509E-3 14 156 3 6292
    phosphotransferase activity, alcohol group as acceptor 8.6451E-3 14 198 3 6292
    glycogen synthase kinase 3 activity 8.8726E-3 14 4 1 6292

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