YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 39 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CBF1
  • nucleus
  • mitochondrion
  • kinetochore
  • methionine biosynthetic process
  • response to drug
  • chromatin assembly or disassembly
  • chromosome segregation
  • DNA binding
  • centromeric DNA binding
  • FYV4
  • mitochondrion
  • telomere maintenance
  • molecular_function
  • MAM33
  • mitochondrial matrix
  • mitochondrion
  • response to drug
  • aerobic respiration
  • molecular_function
  • MRP1
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP10
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP17
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP21
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translational initiation
  • translation
  • structural constituent of ribosome
  • MRP4
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • tRNA binding
  • MRP51
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translational initiation
  • translation
  • structural constituent of ribosome
  • MRPL8
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial genome maintenance
  • translation
  • structural constituent of ribosome
  • MRPS12
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • ribosome
  • translation
  • structural constituent of ribosome
  • MRPS16
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPS17
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPS18
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPS28
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • MRPS35
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPS5
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPS9
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • NAM9
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • NCL1
  • nucleus
  • ribosome biogenesis
  • tRNA methylation
  • tRNA (cytosine-5-)-methyltransferase activity
  • PET123
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RIB4
  • nucleus
  • cytoplasm
  • riboflavin biosynthetic process
  • 6,7-dimethyl-8-ribityllumazine synthase activity
  • RSM10
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM18
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM19
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM22
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM23
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • response to drug
  • translation
  • structural constituent of ribosome
  • RSM24
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • RSM25
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM26
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM27
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • RSM28
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translational initiation
  • translation
  • structural constituent of ribosome
  • RSM7
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • SVL3
  • cellular bud
  • cytoplasm
  • cellular bud neck
  • endocytosis
  • molecular_function
  • SWS2
  • cytoplasm
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • translation
  • structural constituent of ribosome
  • YDR124W
  • cellular_component
  • biological_process
  • molecular_function
  • YJR096W
  • nucleus
  • cytoplasm
  • arabinose catabolic process
  • D-xylose catabolic process
  • aldehyde reductase activity
  • aldo-keto reductase activity
  • YKL151C
  • cytoplasm
  • biological_process
  • molecular_function
  • YSP1
  • mitochondrion
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    organellar small ribosomal subunit 1.5523E-61 39 35 28 6292
    mitochondrial small ribosomal subunit 1.5523E-61 39 35 28 6292
    small ribosomal subunit 2.6519E-48 39 73 28 6292
    organellar ribosome 1.2354E-47 39 90 29 6292
    mitochondrial ribosome 1.2354E-47 39 90 29 6292
    mitochondrial matrix 3.3864E-40 39 176 30 6292
    mitochondrial lumen 3.3864E-40 39 176 30 6292
    ribosomal subunit 1.4295E-37 39 183 29 6292
    ribosome 1.8552E-31 39 290 29 6292
    mitochondrial part 1.0199E-26 39 475 30 6292
    ribonucleoprotein complex 3.9521E-24 39 514 29 6292
    organelle lumen 1.9402E-22 39 660 30 6292
    intracellular organelle lumen 1.9402E-22 39 660 30 6292
    membrane-enclosed lumen 1.1078E-21 39 700 30 6292
    mitochondrion 1.5447E-19 39 1125 33 6292
    non-membrane-bounded organelle 1.1025E-17 39 959 30 6292
    intracellular non-membrane-bounded organelle 1.1025E-17 39 959 30 6292
    macromolecular complex 3.7041E-11 39 1635 30 6292
    cytoplasmic part 7.632E-9 39 2482 33 6292
    organelle part 3.9146E-8 39 2282 31 6292
    intracellular organelle part 3.9146E-8 39 2282 31 6292
    cytoplasm 9.0934E-8 39 3552 37 6292
    membrane-bounded organelle 6.2561E-6 39 3771 36 6292
    intracellular membrane-bounded organelle 6.2561E-6 39 3771 36 6292
    intracellular organelle 6.9542E-5 39 4070 36 6292
    organelle 7.0075E-5 39 4071 36 6292
    intracellular part 8.9674E-4 39 4938 38 6292
    intracellular 1.1631E-3 39 4975 38 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 4.2316E-28 39 376 29 6292
    cellular protein metabolic process 4.3283E-15 39 1074 29 6292
    protein metabolic process 2.0069E-14 39 1136 29 6292
    gene expression 4.4682E-14 39 1283 30 6292
    cellular macromolecule biosynthetic process 6.6231E-14 39 1187 29 6292
    macromolecule biosynthetic process 6.9325E-14 39 1189 29 6292
    cellular biosynthetic process 1.0813E-12 39 1567 31 6292
    biosynthetic process 2.0394E-12 39 1602 31 6292
    cellular macromolecule metabolic process 4.0553E-8 39 2285 31 6292
    cellular metabolic process 4.9049E-8 39 3033 35 6292
    macromolecule metabolic process 8.5E-8 39 2349 31 6292
    metabolic process 1.7358E-7 39 3157 35 6292
    primary metabolic process 6.661E-7 39 2896 33 6292
    cellular process 8.9289E-4 39 4426 36 6292
    aerobic respiration 1.6297E-3 39 83 4 6292
    translational initiation 2.1389E-3 39 42 3 6292
    cellular respiration 2.8878E-3 39 97 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.3615E-35 39 212 29 6292
    structural molecule activity 1.9674E-29 39 339 29 6292
    tRNA (cytosine)-methyltransferase activity 6.1983E-3 39 1 1 6292
    intramolecular transferase activity, transferring acyl groups 6.1983E-3 39 1 1 6292
    tRNA (cytosine-5-)-methyltransferase activity 6.1983E-3 39 1 1 6292
    6,7-dimethyl-8-ribityllumazine synthase activity 6.1983E-3 39 1 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle