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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • KEM1
  • cytoplasm
  • cytoplasmic mRNA processing body
  • nuclear outer membrane
  • filamentous growth
  • response to exogenous dsRNA
  • telomere maintenance
  • traversing start control point of mitotic cell cycle
  • karyogamy involved in conjugation with cellular fusion
  • mRNA catabolic process
  • 5'-3' exoribonuclease activity
  • deoxyribonuclease activity
  • recombinase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 2.1103E-6 7 101 4 6292
    cytosolic part 4.503E-6 7 122 4 6292
    ribosomal subunit 2.2637E-5 7 183 4 6292
    ribonucleoprotein complex 6.5267E-5 7 514 5 6292
    cytosol 1.277E-4 7 284 4 6292
    ribosome 1.3857E-4 7 290 4 6292
    90S preribosome 1.4316E-4 7 17 2 6292
    preribosome 5.8524E-4 7 34 2 6292
    cytosolic small ribosomal subunit 7.3181E-4 7 38 2 6292
    cytosolic large ribosomal subunit 1.8211E-3 7 60 2 6292
    small ribosomal subunit 2.6853E-3 7 73 2 6292
    large ribosomal subunit 6.0062E-3 7 110 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 2.915E-7 7 376 6 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.2282E-5 7 13 2 6292
    cellular protein metabolic process 1.4622E-4 7 1074 6 6292
    protein metabolic process 2.0289E-4 7 1136 6 6292
    cellular macromolecule biosynthetic process 2.6203E-4 7 1187 6 6292
    macromolecule biosynthetic process 2.6461E-4 7 1189 6 6292
    ribosome biogenesis 2.7556E-4 7 346 4 6292
    ribonucleoprotein complex biogenesis 3.725E-4 7 374 4 6292
    gene expression 4.1171E-4 7 1283 6 6292
    cellular macromolecule metabolic process 8.282E-4 7 2285 7 6292
    macromolecule metabolic process 1.0051E-3 7 2349 7 6292
    cellular biosynthetic process 1.3053E-3 7 1567 6 6292
    biosynthetic process 1.4816E-3 7 1602 6 6292
    ribosomal subunit assembly 1.532E-3 7 55 2 6292
    regulation of translation 1.6447E-3 7 57 2 6292
    maturation of SSU-rRNA 1.7614E-3 7 59 2 6292
    posttranscriptional regulation of gene expression 1.8819E-3 7 61 2 6292
    ribosome assembly 2.0698E-3 7 64 2 6292
    regulation of cellular protein metabolic process 2.3339E-3 7 68 2 6292
    organelle assembly 2.4022E-3 7 69 2 6292
    regulation of protein metabolic process 2.7584E-3 7 74 2 6292
    cellular component biogenesis 3.9065E-3 7 694 4 6292
    ribonucleoprotein complex assembly 4.2342E-3 7 92 2 6292
    primary metabolic process 4.3588E-3 7 2896 7 6292
    cellular metabolic process 6.026E-3 7 3033 7 6292
    traversing start control point of mitotic cell cycle 6.6592E-3 7 6 1 6292
    response to exogenous dsRNA 7.7654E-3 7 7 1 6292
    response to dsRNA 7.7654E-3 7 7 1 6292
    metabolic process 7.9792E-3 7 3157 7 6292
    rRNA processing 8.0653E-3 7 128 2 6292
    rRNA metabolic process 9.1999E-3 7 137 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 8.2387E-7 7 212 5 6292
    structural molecule activity 8.4682E-6 7 339 5 6292
    5'-3' exoribonuclease activity 2.224E-3 7 2 1 6292
    nucleic acid binding 3.3506E-3 7 666 4 6292
    recombinase activity 4.4437E-3 7 4 1 6292
    RNA binding 5.7756E-3 7 367 3 6292
    5'-3' exonuclease activity 6.6592E-3 7 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle