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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 14 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ARP7
  • nucleus
  • SWI/SNF complex
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • general RNA polymerase II transcription factor activity
  • ARP9
  • nucleus
  • SWI/SNF complex
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • general RNA polymerase II transcription factor activity
  • HTL1
  • RSC complex
  • chromatin remodeling
  • telomere maintenance
  • response to DNA damage stimulus
  • chromatin binding
  • NPL6
  • nucleus
  • RSC complex
  • chromatin remodeling
  • protein import into nucleus
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • response to DNA damage stimulus
  • DNA-dependent ATPase activity
  • RSC2
  • RSC complex
  • sister chromatid cohesion
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RSC3
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • regulation of transcription, DNA-dependent
  • DNA binding
  • DNA-dependent ATPase activity
  • RSC4
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • RSC58
  • RSC complex
  • chromatin remodeling
  • molecular_function
  • RSC6
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • RSC8
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RSC9
  • RSC complex
  • chromatin remodeling
  • ATP-dependent chromatin remodeling
  • rRNA transcription
  • regulation of transcription from RNA polymerase II promoter
  • DNA-dependent ATPase activity
  • chromatin binding
  • RTT102
  • nucleus
  • SWI/SNF complex
  • RSC complex
  • chromatin remodeling
  • chromosome segregation
  • molecular_function
  • SFH1
  • RSC complex
  • G2/M transition of mitotic cell cycle
  • ATP-dependent chromatin remodeling
  • chromosome segregation
  • chromatin remodeling at centromere
  • double-strand break repair
  • DNA-dependent ATPase activity
  • STH1
  • RSC complex
  • cytoskeleton organization
  • ATP-dependent chromatin remodeling
  • chromosome segregation
  • chromatin remodeling at centromere
  • meiosis
  • double-strand break repair
  • ATPase activity
  • DNA-dependent ATPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RSC complex 2.2492E-38 14 20 14 6292
    chromatin remodeling complex 2.2052E-26 14 99 14 6292
    nuclear part 2.4173E-11 14 1103 14 6292
    protein complex 3.7067E-11 14 1137 14 6292
    macromolecular complex 6.1412E-9 14 1635 14 6292
    nucleus 1.3856E-7 14 2041 14 6292
    organelle part 6.6422E-7 14 2282 14 6292
    intracellular organelle part 6.6422E-7 14 2282 14 6292
    SWI/SNF complex 2.476E-6 14 13 3 6292
    SWI/SNF-type complex 2.476E-6 14 13 3 6292
    membrane-bounded organelle 7.6409E-4 14 3771 14 6292
    intracellular membrane-bounded organelle 7.6409E-4 14 3771 14 6292
    intracellular organelle 2.2276E-3 14 4070 14 6292
    organelle 2.2353E-3 14 4071 14 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    chromatin remodeling 7.1513E-29 14 68 14 6292
    ATP-dependent chromatin remodeling 1.8386E-25 14 26 11 6292
    chromatin modification 5.4421E-23 14 168 14 6292
    chromatin organization 8.4926E-22 14 203 14 6292
    chromosome organization 1.4844E-15 14 555 14 6292
    organelle organization 3.2732E-11 14 1127 14 6292
    cellular component organization 3.8644E-9 14 1582 14 6292
    chromatin remodeling at centromere 4.5979E-6 14 2 2 6292
    double-strand break repair 5.6643E-6 14 57 4 6292
    response to DNA damage stimulus 6.0956E-6 14 236 6 6292
    cellular response to stress 1.9988E-5 14 290 6 6292
    cellular response to stimulus 9.1141E-5 14 379 6 6292
    chromosome segregation 1.3967E-4 14 128 4 6292
    response to stress 4.086E-4 14 497 6 6292
    DNA repair 6.6151E-4 14 192 4 6292
    DNA metabolic process 9.8552E-4 14 585 6 6292
    double-strand break repair via nonhomologous end joining 1.3396E-3 14 25 2 6292
    non-recombinational repair 2.4766E-3 14 34 2 6292
    response to stimulus 4.0359E-3 14 766 6 6292
    nucleic acid metabolic process 5.169E-3 14 1415 8 6292
    rRNA transcription 6.6614E-3 14 3 1 6292
    cellular process 7.2188E-3 14 4426 14 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.9462E-3 14 1566 8 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA-dependent ATPase activity 2.8113E-21 14 55 11 6292
    ATPase activity, coupled 3.1085E-16 14 149 11 6292
    ATPase activity 1.5546E-14 14 211 11 6292
    nucleoside-triphosphatase activity 2.1483E-12 14 329 11 6292
    hydrolase activity, acting on acid anhydrides 4.6634E-12 14 353 11 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.6634E-12 14 353 11 6292
    pyrophosphatase activity 4.6634E-12 14 353 11 6292
    hydrolase activity 1.3284E-7 14 911 11 6292
    catalytic activity 8.6733E-4 14 2150 11 6292
    chromatin binding 2.3339E-3 14 33 2 6292
    general RNA polymerase II transcription factor activity 8.567E-3 14 64 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle