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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitochondrial pyruvate dehydrogenase complex 4.8197E-10 3 6 3 6292
pyruvate dehydrogenase complex 4.8197E-10 3 6 3 6292
mitochondrial matrix 2.1525E-5 3 176 3 6292
mitochondrial lumen 2.1525E-5 3 176 3 6292
nucleoid 4.9138E-5 3 26 2 6292
mitochondrial nucleoid 4.9138E-5 3 26 2 6292
mitochondrial part 4.2773E-4 3 475 3 6292
organelle lumen 1.1495E-3 3 660 3 6292
intracellular organelle lumen 1.1495E-3 3 660 3 6292
membrane-enclosed lumen 1.3717E-3 3 700 3 6292
mitochondrial oxoglutarate dehydrogenase complex 1.4299E-3 3 3 1 6292
oxoglutarate dehydrogenase complex 1.4299E-3 3 3 1 6292
glycine cleavage complex 2.8585E-3 3 6 1 6292
mitochondrion 5.7035E-3 3 1125 3 6292
protein complex 5.8881E-3 3 1137 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

pyruvate metabolic process 3.1916E-7 3 44 3 6292
monocarboxylic acid metabolic process 9.4487E-6 3 134 3 6292
organic acid metabolic process 1.4698E-4 3 333 3 6292
oxoacid metabolic process 1.4698E-4 3 333 3 6292
carboxylic acid metabolic process 1.4698E-4 3 333 3 6292
cellular ketone metabolic process 1.6493E-4 3 346 3 6292
valine catabolic process 4.768E-4 3 1 1 6292
valine metabolic process 4.768E-4 3 1 1 6292
isoleucine catabolic process 4.768E-4 3 1 1 6292
acetyl-CoA biosynthetic process from pyruvate 9.5344E-4 3 2 1 6292
L-serine metabolic process 9.5344E-4 3 2 1 6292
L-serine biosynthetic process 9.5344E-4 3 2 1 6292
leucine catabolic process 9.5344E-4 3 2 1 6292
isoleucine metabolic process 1.4299E-3 3 3 1 6292
small molecule metabolic process 1.7562E-3 3 760 3 6292
acetyl-CoA biosynthetic process 1.9063E-3 3 4 1 6292
branched chain family amino acid catabolic process 1.9063E-3 3 4 1 6292
glycine catabolic process 2.8585E-3 3 6 1 6292
serine family amino acid catabolic process 3.8101E-3 3 8 1 6292
glycine metabolic process 3.8101E-3 3 8 1 6292
leucine metabolic process 3.8101E-3 3 8 1 6292
serine family amino acid biosynthetic process 5.7116E-3 3 12 1 6292
branched chain family amino acid metabolic process 8.5592E-3 3 18 1 6292
acetyl-CoA metabolic process 9.5071E-3 3 20 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

pyruvate dehydrogenase (acetyl-transferring) activity 9.0929E-7 3 4 2 6292
pyruvate dehydrogenase activity 9.0929E-7 3 4 2 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 1.5153E-6 3 5 2 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors 4.5363E-5 3 25 2 6292
dihydrolipoyllysine-residue acetyltransferase activity 4.768E-4 3 1 1 6292
dihydrolipoyl dehydrogenase activity 4.768E-4 3 1 1 6292
dihydrolipoamide S-acyltransferase activity 4.768E-4 3 1 1 6292
S-acetyltransferase activity 9.5344E-4 3 2 1 6292
oxoglutarate dehydrogenase (succinyl-transferring) activity 9.5344E-4 3 2 1 6292
glycine dehydrogenase (decarboxylating) activity 2.8585E-3 3 6 1 6292
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 2.8585E-3 3 6 1 6292
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 3.3344E-3 3 7 1 6292
oxidoreductase activity, acting on the CH-NH2 group of donors 5.7116E-3 3 12 1 6292
oxidoreductase activity 5.7868E-3 3 281 2 6292
S-acyltransferase activity 6.1865E-3 3 13 1 6292
oxidoreductase activity, acting on sulfur group of donors 9.5071E-3 3 20 1 6292
oxidoreductase activity, acting on NADH or NADPH 9.9809E-3 3 21 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle