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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS13
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS17A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS24A, RPS24B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • mitochondrion
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • nucleotide binding
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.0185E-10 7 101 6 6292
    cytosolic small ribosomal subunit 1.2735E-10 7 38 5 6292
    cytosolic part 3.2391E-10 7 122 6 6292
    small ribosomal subunit 3.7754E-9 7 73 5 6292
    ribosomal subunit 3.8154E-9 7 183 6 6292
    ribonucleoprotein complex 2.338E-8 7 514 7 6292
    cytosol 5.413E-8 7 284 6 6292
    ribosome 6.138E-8 7 290 6 6292
    90S preribosome 5.6973E-7 7 17 3 6292
    preribosome 4.973E-6 7 34 3 6292
    non-membrane-bounded organelle 7.5345E-5 7 959 6 6292
    intracellular non-membrane-bounded organelle 7.5345E-5 7 959 6 6292
    macromolecular complex 7.9244E-5 7 1635 7 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 2.5814E-9 7 376 7 6292
    regulation of translation 2.0765E-7 7 57 4 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.4008E-7 7 13 3 6292
    posttranscriptional regulation of gene expression 2.7391E-7 7 61 4 6292
    regulation of cellular protein metabolic process 4.263E-7 7 68 4 6292
    regulation of protein metabolic process 6.0093E-7 7 74 4 6292
    cellular protein metabolic process 4.1538E-6 7 1074 7 6292
    protein metabolic process 6.1593E-6 7 1136 7 6292
    cellular macromolecule biosynthetic process 8.3828E-6 7 1187 7 6292
    macromolecule biosynthetic process 8.4824E-6 7 1189 7 6292
    gene expression 1.4468E-5 7 1283 7 6292
    maturation of SSU-rRNA 2.6695E-5 7 59 3 6292
    cellular biosynthetic process 5.8828E-5 7 1567 7 6292
    biosynthetic process 6.8686E-5 7 1602 7 6292
    ribosomal small subunit assembly 9.5944E-5 7 14 2 6292
    rRNA processing 2.7117E-4 7 128 3 6292
    ribosome biogenesis 2.7556E-4 7 346 4 6292
    rRNA metabolic process 3.3156E-4 7 137 3 6292
    ribosomal small subunit biogenesis 3.4048E-4 7 26 2 6292
    ribonucleoprotein complex biogenesis 3.725E-4 7 374 4 6292
    regulation of gene expression 7.2752E-4 7 445 4 6292
    regulation of macromolecule biosynthetic process 7.9889E-4 7 456 4 6292
    cellular macromolecule metabolic process 8.282E-4 7 2285 7 6292
    regulation of cellular biosynthetic process 9.1156E-4 7 472 4 6292
    regulation of biosynthetic process 9.1897E-4 7 473 4 6292
    macromolecule metabolic process 1.0051E-3 7 2349 7 6292
    regulation of macromolecule metabolic process 1.0353E-3 7 488 4 6292
    ncRNA processing 1.2438E-3 7 215 3 6292
    regulation of primary metabolic process 1.2617E-3 7 514 4 6292
    regulation of cellular metabolic process 1.4794E-3 7 536 4 6292
    ribosomal subunit assembly 1.532E-3 7 55 2 6292
    regulation of metabolic process 1.5978E-3 7 547 4 6292
    ribosome assembly 2.0698E-3 7 64 2 6292
    ncRNA metabolic process 2.0862E-3 7 257 3 6292
    organelle assembly 2.4022E-3 7 69 2 6292
    cellular component biogenesis 3.9065E-3 7 694 4 6292
    biological regulation 3.9225E-3 7 1213 5 6292
    ribonucleoprotein complex assembly 4.2342E-3 7 92 2 6292
    primary metabolic process 4.3588E-3 7 2896 7 6292
    cellular metabolic process 6.026E-3 7 3033 7 6292
    RNA processing 6.3721E-3 7 380 3 6292
    regulation of cellular process 6.4862E-3 7 796 4 6292
    regulation of biological process 7.3628E-3 7 824 4 6292
    metabolic process 7.9792E-3 7 3157 7 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.4752E-11 7 212 7 6292
    structural molecule activity 1.2424E-9 7 339 7 6292
    rRNA binding 1.2639E-4 7 16 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle