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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL4B
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPP0
  • ribosomal large subunit assembly
  • translational elongation
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    preribosome 2.6145E-9 12 34 5 6292
    cytosolic ribosome 1.2596E-8 12 101 6 6292
    90S preribosome 1.782E-8 12 17 4 6292
    cytosolic part 3.9481E-8 12 122 6 6292
    ribosomal subunit 4.4578E-7 12 183 6 6292
    cytosolic small ribosomal subunit 5.4096E-7 12 38 4 6292
    ribonucleoprotein complex 6.9393E-7 12 514 8 6292
    cytosol 5.8922E-6 12 284 6 6292
    ribosome 6.6531E-6 12 290 6 6292
    small ribosomal subunit 7.696E-6 12 73 4 6292
    macromolecular complex 3.593E-3 12 1635 8 6292
    non-membrane-bounded organelle 4.9929E-3 12 959 6 6292
    intracellular non-membrane-bounded organelle 4.9929E-3 12 959 6 6292
    cytosolic large ribosomal subunit 5.5506E-3 12 60 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.7552E-15 12 376 12 6292
    cellular protein metabolic process 5.8125E-10 12 1074 12 6292
    protein metabolic process 1.1437E-9 12 1136 12 6292
    cellular macromolecule biosynthetic process 1.9421E-9 12 1187 12 6292
    macromolecule biosynthetic process 1.9819E-9 12 1189 12 6292
    gene expression 4.9591E-9 12 1283 12 6292
    cellular biosynthetic process 5.5155E-8 12 1567 12 6292
    biosynthetic process 7.1963E-8 12 1602 12 6292
    cellular macromolecule metabolic process 5.1661E-6 12 2285 12 6292
    macromolecule metabolic process 7.2022E-6 12 2349 12 6292
    primary metabolic process 8.9282E-5 12 2896 12 6292
    cellular metabolic process 1.5563E-4 12 3033 12 6292
    metabolic process 2.5194E-4 12 3157 12 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.571E-4 12 13 2 6292
    ribosome biogenesis 3.1264E-3 12 346 4 6292
    ribonucleoprotein complex biogenesis 4.1497E-3 12 374 4 6292
    ribosomal subunit assembly 4.6816E-3 12 55 2 6292
    regulation of translation 5.0209E-3 12 57 2 6292
    maturation of SSU-rRNA 5.3712E-3 12 59 2 6292
    posttranscriptional regulation of gene expression 5.7327E-3 12 61 2 6292
    ribosome assembly 6.2953E-3 12 64 2 6292
    regulation of cellular protein metabolic process 7.0833E-3 12 68 2 6292
    organelle assembly 7.2871E-3 12 69 2 6292
    regulation of protein metabolic process 8.3454E-3 12 74 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 5.7344E-16 12 212 11 6292
    structural molecule activity 1.0864E-13 12 339 11 6292
    rRNA binding 3.9428E-4 12 16 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle