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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    preribosome 1.4126E-11 12 34 6 6292
    90S preribosome 5.9069E-11 12 17 5 6292
    cytosolic ribosome 1.652E-10 12 101 7 6292
    cytosolic part 6.3389E-10 12 122 7 6292
    ribonucleoprotein complex 6.9243E-10 12 514 10 6292
    cytosolic small ribosomal subunit 4.6987E-9 12 38 5 6292
    ribosomal subunit 1.1004E-8 12 183 7 6292
    small ribosomal subunit 1.3609E-7 12 73 5 6292
    cytosol 2.3132E-7 12 284 7 6292
    ribosome 2.6703E-7 12 290 7 6292
    non-membrane-bounded organelle 6.103E-6 12 959 9 6292
    intracellular non-membrane-bounded organelle 6.103E-6 12 959 9 6292
    macromolecular complex 5.3141E-5 12 1635 10 6292
    cytosolic large ribosomal subunit 5.5506E-3 12 60 2 6292
    nucleolus 6.5368E-3 12 211 3 6292
    intracellular organelle part 7.3047E-3 12 2282 9 6292
    organelle part 7.3047E-3 12 2282 9 6292
    small nucleolar ribonucleoprotein complex 7.9142E-3 12 72 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 3.0688E-11 12 376 10 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.3753E-9 12 13 4 6292
    gene expression 2.393E-7 12 1283 11 6292
    ribosome biogenesis 8.9294E-7 12 346 7 6292
    cellular protein metabolic process 9.5815E-7 12 1074 10 6292
    ribonucleoprotein complex biogenesis 1.5153E-6 12 374 7 6292
    protein metabolic process 1.6479E-6 12 1136 10 6292
    cellular macromolecule biosynthetic process 2.516E-6 12 1187 10 6292
    macromolecule biosynthetic process 2.5571E-6 12 1189 10 6292
    maturation of SSU-rRNA 3.2646E-6 12 59 4 6292
    cellular biosynthetic process 3.5603E-5 12 1567 10 6292
    biosynthetic process 4.3855E-5 12 1602 10 6292
    rRNA processing 7.1288E-5 12 128 4 6292
    cellular component biogenesis 9.277E-5 12 694 7 6292
    rRNA metabolic process 9.2981E-5 12 137 4 6292
    cellular macromolecule metabolic process 1.144E-4 12 2285 11 6292
    macromolecule metabolic process 1.5296E-4 12 2349 11 6292
    ncRNA processing 5.2873E-4 12 215 4 6292
    ncRNA metabolic process 1.0381E-3 12 257 4 6292
    primary metabolic process 1.3504E-3 12 2896 11 6292
    cellular metabolic process 2.1697E-3 12 3033 11 6292
    metabolic process 3.2647E-3 12 3157 11 6292
    RNA processing 4.3958E-3 12 380 4 6292
    ribosomal subunit assembly 4.6816E-3 12 55 2 6292
    regulation of translation 5.0209E-3 12 57 2 6292
    posttranscriptional regulation of gene expression 5.7327E-3 12 61 2 6292
    ribosome assembly 6.2953E-3 12 64 2 6292
    regulation of cellular protein metabolic process 7.0833E-3 12 68 2 6292
    organelle assembly 7.2871E-3 12 69 2 6292
    regulation of protein metabolic process 8.3454E-3 12 74 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 9.5227E-14 12 212 10 6292
    structural molecule activity 1.0869E-11 12 339 10 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle