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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS24A, RPS24B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • mitochondrion
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • nucleotide binding
  • structural constituent of ribosome
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 2.5698E-11 10 101 7 6292
    cytosolic part 9.9194E-11 10 122 7 6292
    cytosolic small ribosomal subunit 1.5082E-9 10 38 5 6292
    ribosomal subunit 1.7519E-9 10 183 7 6292
    90S preribosome 7.585E-9 10 17 4 6292
    cytosol 3.7911E-8 10 284 7 6292
    ribosome 4.384E-8 10 290 7 6292
    small ribosomal subunit 4.4091E-8 10 73 5 6292
    ribonucleoprotein complex 7.3162E-8 10 514 8 6292
    preribosome 1.4589E-7 10 34 4 6292
    non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    intracellular non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    macromolecular complex 5.4804E-4 10 1635 8 6292
    cytosolic large ribosomal subunit 3.8312E-3 10 60 2 6292
    organelle part 6.1675E-3 10 2282 8 6292
    intracellular organelle part 6.1675E-3 10 2282 8 6292
    small-subunit processome 9.5019E-3 10 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 8.4087E-11 10 376 9 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.2857E-9 10 13 4 6292
    cellular protein metabolic process 1.0138E-6 10 1074 9 6292
    regulation of translation 1.2209E-6 10 57 4 6292
    maturation of SSU-rRNA 1.4045E-6 10 59 4 6292
    posttranscriptional regulation of gene expression 1.608E-6 10 61 4 6292
    protein metabolic process 1.6655E-6 10 1136 9 6292
    cellular macromolecule biosynthetic process 2.4546E-6 10 1187 9 6292
    macromolecule biosynthetic process 2.4913E-6 10 1189 9 6292
    regulation of cellular protein metabolic process 2.4959E-6 10 68 4 6292
    regulation of protein metabolic process 3.5102E-6 10 74 4 6292
    ribosome biogenesis 4.61E-6 10 346 6 6292
    gene expression 4.872E-6 10 1283 9 6292
    ribonucleoprotein complex biogenesis 7.2602E-6 10 374 6 6292
    cellular biosynthetic process 2.8141E-5 10 1567 9 6292
    rRNA processing 3.1217E-5 10 128 4 6292
    biosynthetic process 3.4126E-5 10 1602 9 6292
    rRNA metabolic process 4.0811E-5 10 137 4 6292
    ncRNA processing 2.3677E-4 10 215 4 6292
    cellular component biogenesis 2.5043E-4 10 694 6 6292
    ncRNA metabolic process 4.6994E-4 10 257 4 6292
    cellular macromolecule metabolic process 7.3309E-4 10 2285 9 6292
    macromolecule metabolic process 9.2762E-4 10 2349 9 6292
    RNA processing 2.0543E-3 10 380 4 6292
    regulation of gene expression 3.6771E-3 10 445 4 6292
    regulation of macromolecule biosynthetic process 4.0203E-3 10 456 4 6292
    regulation of cellular biosynthetic process 4.5583E-3 10 472 4 6292
    regulation of biosynthetic process 4.5935E-3 10 473 4 6292
    regulation of macromolecule metabolic process 5.1444E-3 10 488 4 6292
    primary metabolic process 5.4001E-3 10 2896 9 6292
    regulation of primary metabolic process 6.2046E-3 10 514 4 6292
    regulation of cellular metabolic process 7.2118E-3 10 536 4 6292
    regulation of metabolic process 7.755E-3 10 547 4 6292
    cellular metabolic process 7.9165E-3 10 3033 9 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.6009E-13 10 212 9 6292
    structural molecule activity 3.2934E-11 10 339 9 6292
    rRNA binding 2.6962E-4 10 16 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle