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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL4B
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPP0
  • ribosomal large subunit assembly
  • translational elongation
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • STM1
  • cytoplasm
  • nuclear telomere cap complex
  • anti-apoptosis
  • telomere maintenance
  • DNA binding
  • telomeric DNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 6.3807E-9 11 101 6 6292
    cytosolic part 2.0058E-8 11 122 6 6292
    preribosome 2.2838E-7 11 34 4 6292
    ribosomal subunit 2.2839E-7 11 183 6 6292
    ribonucleoprotein complex 2.4909E-7 11 514 8 6292
    90S preribosome 2.668E-6 11 17 3 6292
    cytosol 3.0618E-6 11 284 6 6292
    ribosome 3.4601E-6 11 290 6 6292
    cytosolic small ribosomal subunit 3.2441E-5 11 38 3 6292
    cytosolic large ribosomal subunit 1.2885E-4 11 60 3 6292
    macromolecular complex 1.7215E-4 11 1635 9 6292
    small ribosomal subunit 2.3129E-4 11 73 3 6292
    non-membrane-bounded organelle 3.5121E-4 11 959 7 6292
    intracellular non-membrane-bounded organelle 3.5121E-4 11 959 7 6292
    large ribosomal subunit 7.7458E-4 11 110 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 5.4005E-12 11 376 10 6292
    cellular protein metabolic process 1.8871E-7 11 1074 10 6292
    protein metabolic process 3.2802E-7 11 1136 10 6292
    cellular macromolecule biosynthetic process 5.0526E-7 11 1187 10 6292
    macromolecule biosynthetic process 5.137E-7 11 1189 10 6292
    gene expression 1.0844E-6 11 1283 10 6292
    cellular biosynthetic process 7.6547E-6 11 1567 10 6292
    biosynthetic process 9.4905E-6 11 1602 10 6292
    cellular macromolecule metabolic process 1.4269E-5 11 2285 11 6292
    macromolecule metabolic process 1.9349E-5 11 2349 11 6292
    ribosomal subunit assembly 9.9258E-5 11 55 3 6292
    ribosome assembly 1.5628E-4 11 64 3 6292
    primary metabolic process 1.9438E-4 11 2896 11 6292
    organelle assembly 1.9559E-4 11 69 3 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.145E-4 11 13 2 6292
    cellular metabolic process 3.2347E-4 11 3033 11 6292
    ribonucleoprotein complex assembly 4.5856E-4 11 92 3 6292
    metabolic process 5.03E-4 11 3157 11 6292
    negative regulation of programmed cell death 1.7483E-3 11 1 1 6292
    anti-apoptosis 1.7483E-3 11 1 1 6292
    negative regulation of cell death 1.7483E-3 11 1 1 6292
    negative regulation of apoptosis 1.7483E-3 11 1 1 6292
    ribosome biogenesis 2.1778E-3 11 346 4 6292
    ribosomal large subunit assembly 2.1955E-3 11 41 2 6292
    ribonucleoprotein complex biogenesis 2.9012E-3 11 374 4 6292
    cellular macromolecular complex assembly 3.3093E-3 11 182 3 6292
    regulation of translation 4.2084E-3 11 57 2 6292
    maturation of SSU-rRNA 4.5031E-3 11 59 2 6292
    posttranscriptional regulation of gene expression 4.8071E-3 11 61 2 6292
    ribosomal large subunit biogenesis 5.443E-3 11 65 2 6292
    regulation of cellular protein metabolic process 5.9441E-3 11 68 2 6292
    regulation of programmed cell death 6.9763E-3 11 4 1 6292
    regulation of apoptosis 6.9763E-3 11 4 1 6292
    regulation of cell death 6.9763E-3 11 4 1 6292
    regulation of protein metabolic process 7.0076E-3 11 74 2 6292
    cellular macromolecular complex subunit organization 8.8966E-3 11 259 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.6349E-14 11 212 10 6292
    structural molecule activity 1.9021E-12 11 339 10 6292
    rRNA binding 3.2905E-4 11 16 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle