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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ADA2
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • transcription coactivator activity
  • HFI1
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • telomere maintenance
  • transcription from RNA polymerase II promoter
  • histone acetylation
  • transcription cofactor activity
  • transcription coactivator activity
  • NGG1
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • response to drug
  • histone acetylation
  • transcription cofactor activity
  • SGF73
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • histone acetyltransferase activity
  • structural molecule activity
  • SPT7
  • SLIK (SAGA-like) complex
  • mitochondrion
  • SAGA complex
  • chromatin modification
  • protein complex assembly
  • conjugation with cellular fusion
  • histone acetylation
  • structural molecule activity
  • TAF1
  • transcription factor TFIID complex
  • protein amino acid phosphorylation
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • histone acetyltransferase activity
  • general RNA polymerase II transcription factor activity
  • protein serine/threonine kinase activity
  • TAF10
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF11
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF12
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF3
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF4
  • transcription factor TFIID complex
  • transcription from RNA polymerase II promoter
  • RNA polymerase II transcription factor activity
  • TAF5
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF6
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF7
  • nucleus
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF9
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription factor TFIID complex 3.3769E-25 15 15 10 6292
    SLIK (SAGA-like) complex 8.9986E-25 15 16 10 6292
    SAGA complex 7.2349E-23 15 22 10 6292
    SAGA-type complex 1.2791E-22 15 23 10 6292
    nucleoplasm part 4.7098E-22 15 245 15 6292
    nucleoplasm 1.4911E-21 15 264 15 6292
    histone acetyltransferase complex 2.7321E-19 15 44 10 6292
    DNA-directed RNA polymerase II, holoenzyme 3.8866E-18 15 56 10 6292
    nuclear lumen 5.8229E-18 15 453 15 6292
    transcription factor complex 4.9851E-17 15 71 10 6292
    organelle lumen 1.7741E-15 15 660 15 6292
    intracellular organelle lumen 1.7741E-15 15 660 15 6292
    membrane-enclosed lumen 4.3281E-15 15 700 15 6292
    nuclear part 4.193E-12 15 1103 15 6292
    protein complex 6.6306E-12 15 1137 15 6292
    macromolecular complex 1.5857E-9 15 1635 15 6292
    nucleus 4.4738E-8 15 2041 15 6292
    Ada2/Gcn5/Ada3 transcription activator complex 1.0934E-7 15 5 3 6292
    organelle part 2.3996E-7 15 2282 15 6292
    intracellular organelle part 2.3996E-7 15 2282 15 6292
    membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular organelle 1.4392E-3 15 4070 15 6292
    organelle 1.4445E-3 15 4071 15 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    regulation of transcription involved in G1 phase of mitotic cell cycle 2.3559E-22 15 14 9 6292
    histone acetylation 2.8152E-20 15 36 10 6292
    protein amino acid acetylation 4.4819E-19 15 46 10 6292
    G1 phase of mitotic cell cycle 5.4539E-19 15 27 9 6292
    G1 phase 5.4539E-19 15 27 9 6292
    protein amino acid acylation 6.8429E-18 15 59 10 6292
    transcription initiation from RNA polymerase II promoter 1.5585E-16 15 47 9 6292
    covalent chromatin modification 4.813E-16 15 88 10 6292
    histone modification 4.813E-16 15 88 10 6292
    transcription initiation 1.2064E-15 15 58 9 6292
    interphase of mitotic cell cycle 1.5652E-13 15 97 9 6292
    interphase 1.5652E-13 15 97 9 6292
    protein complex biogenesis 1.6646E-13 15 155 10 6292
    protein complex assembly 1.6646E-13 15 155 10 6292
    chromatin modification 3.7763E-13 15 168 10 6292
    chromatin organization 2.5611E-12 15 203 10 6292
    transcription from RNA polymerase II promoter 9.3663E-12 15 335 11 6292
    post-translational protein modification 1.8795E-11 15 357 11 6292
    macromolecular complex assembly 6.6474E-11 15 281 10 6292
    regulation of transcription from RNA polymerase II promoter 3.8172E-10 15 228 9 6292
    macromolecular complex subunit organization 7.119E-10 15 357 10 6292
    protein modification process 7.1595E-10 15 499 11 6292
    transcription, DNA-dependent 7.8041E-10 15 503 11 6292
    RNA biosynthetic process 8.6833E-10 15 508 11 6292
    mitotic cell cycle 1.0381E-9 15 255 9 6292
    cellular component assembly 1.4967E-9 15 385 10 6292
    transcription 2.1245E-9 15 552 11 6292
    macromolecule modification 2.9431E-9 15 569 11 6292
    regulation of transcription, DNA-dependent 2.0903E-8 15 358 9 6292
    regulation of RNA metabolic process 2.3609E-8 15 363 9 6292
    cell cycle phase 3.2138E-8 15 376 9 6292
    regulation of transcription 3.8641E-8 15 384 9 6292
    cellular component organization 4.4453E-8 15 1582 14 6292
    chromosome organization 5.2737E-8 15 555 10 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 7.6095E-8 15 415 9 6292
    regulation of nitrogen compound metabolic process 7.7707E-8 15 416 9 6292
    regulation of gene expression 1.3959E-7 15 445 9 6292
    regulation of macromolecule biosynthetic process 1.725E-7 15 456 9 6292
    regulation of cellular biosynthetic process 2.3249E-7 15 472 9 6292
    regulation of biosynthetic process 2.3678E-7 15 473 9 6292
    cellular macromolecule metabolic process 2.4475E-7 15 2285 15 6292
    regulation of macromolecule metabolic process 3.1004E-7 15 488 9 6292
    cell cycle process 3.2117E-7 15 490 9 6292
    macromolecule metabolic process 3.7086E-7 15 2349 15 6292
    cellular component biogenesis 4.4887E-7 15 694 10 6292
    regulation of primary metabolic process 4.8478E-7 15 514 9 6292
    cell cycle 5.8149E-7 15 525 9 6292
    regulation of cellular metabolic process 6.9469E-7 15 536 9 6292
    RNA metabolic process 7.0041E-7 15 954 11 6292
    regulation of metabolic process 8.2673E-7 15 547 9 6292
    cellular protein metabolic process 2.3916E-6 15 1074 11 6292
    protein metabolic process 4.26E-6 15 1136 11 6292
    cellular macromolecule biosynthetic process 6.678E-6 15 1187 11 6292
    macromolecule biosynthetic process 6.7939E-6 15 1189 11 6292
    primary metabolic process 8.6423E-6 15 2896 15 6292
    gene expression 1.4731E-5 15 1283 11 6292
    cellular metabolic process 1.7316E-5 15 3033 15 6292
    regulation of cellular process 1.9525E-5 15 796 9 6292
    regulation of biological process 2.5982E-5 15 824 9 6292
    metabolic process 3.1628E-5 15 3157 15 6292
    nucleic acid metabolic process 3.9489E-5 15 1415 11 6292
    organelle organization 4.1023E-5 15 1127 10 6292
    biological regulation 7.9692E-5 15 1213 10 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.0815E-4 15 1566 11 6292
    cellular biosynthetic process 1.0883E-4 15 1567 11 6292
    biosynthetic process 1.3527E-4 15 1602 11 6292
    cellular nitrogen compound metabolic process 3.5742E-4 15 1770 11 6292
    nitrogen compound metabolic process 4.0047E-4 15 1791 11 6292
    cellular process 5.0732E-3 15 4426 15 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription regulator activity 2.4594E-15 15 339 13 6292
    general RNA polymerase II transcription factor activity 3.1039E-15 15 64 9 6292
    RNA polymerase II transcription factor activity 2.7545E-14 15 130 10 6292
    transcription cofactor activity 1.0274E-4 15 40 3 6292
    transcription factor binding 1.2778E-4 15 43 3 6292
    histone acetyltransferase activity 7.0676E-4 15 17 2 6292
    lysine N-acetyltransferase activity 7.0676E-4 15 17 2 6292
    transcription coactivator activity 1.0853E-3 15 21 2 6292
    N-acetyltransferase activity 2.6841E-3 15 33 2 6292
    N-acyltransferase activity 3.5492E-3 15 38 2 6292
    acetyltransferase activity 6.0833E-3 15 50 2 6292
    transcription activator activity 8.9514E-3 15 61 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle