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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
DHH1
  • cytoplasm
  • cytoplasmic mRNA processing body
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • deadenylation-dependent decapping of nuclear-transcribed mRNA
  • protein binding
  • RNA helicase activity
  • KEM1
  • cytoplasm
  • cytoplasmic mRNA processing body
  • nuclear outer membrane
  • filamentous growth
  • response to exogenous dsRNA
  • telomere maintenance
  • traversing start control point of mitotic cell cycle
  • karyogamy involved in conjugation with cellular fusion
  • mRNA catabolic process
  • 5'-3' exoribonuclease activity
  • deoxyribonuclease activity
  • recombinase activity
  • LSM1
  • mRNA cap binding complex
  • cytoplasmic mRNA processing body
  • deadenylation-dependent decapping of nuclear-transcribed mRNA
  • mRNA catabolic process
  • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • RNA binding
  • RNA cap binding
  • LSM2
  • U4/U6 x U5 tri-snRNP complex
  • nucleolus
  • U6 snRNP
  • small nucleolar ribonucleoprotein complex
  • mRNA catabolic process
  • nuclear mRNA splicing, via spliceosome
  • RNA binding
  • LSM4
  • U4/U6 x U5 tri-snRNP complex
  • nucleolus
  • U6 snRNP
  • small nucleolar ribonucleoprotein complex
  • mRNA catabolic process
  • nuclear mRNA splicing, via spliceosome
  • RNA binding
  • LSM6
  • U4/U6 x U5 tri-snRNP complex
  • nucleolus
  • U6 snRNP
  • small nucleolar ribonucleoprotein complex
  • mRNA catabolic process
  • nuclear mRNA splicing, via spliceosome
  • RNA binding
  • LSM7
  • U4/U6 x U5 tri-snRNP complex
  • nucleolus
  • U6 snRNP
  • small nucleolar ribonucleoprotein complex
  • telomere maintenance
  • mRNA catabolic process
  • nuclear mRNA splicing, via spliceosome
  • RNA binding
  • PAT1
  • cytoplasmic mRNA processing body
  • deadenylation-dependent decapping of nuclear-transcribed mRNA
  • chromosome segregation
  • regulation of translational initiation
  • molecular_function
  • PRP4
  • U4/U6 x U5 tri-snRNP complex
  • nuclear mRNA splicing, via spliceosome
  • molecular_function
  • SNU114
  • U4/U6 x U5 tri-snRNP complex
  • U5 snRNP
  • generation of catalytic spliceosome for first transesterification step
  • nuclear mRNA splicing, via spliceosome
  • GTP binding
  • U5 snRNA binding
  • GTPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    U4/U6 x U5 tri-snRNP complex 2.1823E-12 10 32 6 6292
    ribonucleoprotein complex 1.2207E-11 10 514 10 6292
    small nuclear ribonucleoprotein complex 1.6087E-10 10 63 6 6292
    U6 snRNP 1.0565E-9 10 11 4 6292
    cytoplasmic mRNA processing body 4.3568E-9 10 15 4 6292
    macromolecular complex 1.3754E-6 10 1635 10 6292
    small nucleolar ribonucleoprotein complex 3.1433E-6 10 72 4 6292
    nucleolus 2.202E-4 10 211 4 6292
    nuclear part 3.6626E-4 10 1103 7 6292
    nuclear lumen 3.9246E-3 10 453 4 6292
    mRNA cap binding complex 4.7611E-3 10 3 1 6292
    RNA cap binding complex 9.5019E-3 10 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA metabolic process 1.6065E-15 10 213 10 6292
    mRNA catabolic process 6.0969E-15 10 69 8 6292
    RNA catabolic process 2.1071E-14 10 80 8 6292
    cellular macromolecule catabolic process 3.7352E-10 10 265 8 6292
    macromolecule catabolic process 8.5908E-10 10 294 8 6292
    nuclear mRNA splicing, via spliceosome 2.6008E-9 10 99 6 6292
    RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 2.7653E-9 10 100 6 6292
    RNA splicing, via transesterification reactions 4.1763E-9 10 107 6 6292
    RNA metabolic process 6.1681E-9 10 954 10 6292
    cellular catabolic process 1.3436E-8 10 415 8 6292
    RNA splicing 1.4922E-8 10 132 6 6292
    mRNA processing 4.0844E-8 10 156 6 6292
    catabolic process 5.5201E-8 10 496 8 6292
    nucleic acid metabolic process 3.2281E-7 10 1415 10 6292
    deadenylation-dependent decapping of nuclear-transcribed mRNA 4.7397E-7 10 11 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.9255E-7 10 1566 10 6292
    cellular nitrogen compound metabolic process 3.0471E-6 10 1770 10 6292
    nitrogen compound metabolic process 3.4296E-6 10 1791 10 6292
    RNA processing 7.9654E-6 10 380 6 6292
    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 8.2906E-6 10 27 3 6292
    nuclear-transcribed mRNA catabolic process 2.3692E-5 10 38 3 6292
    cellular macromolecule metabolic process 3.9402E-5 10 2285 10 6292
    macromolecule metabolic process 5.1966E-5 10 2349 10 6292
    primary metabolic process 4.2311E-4 10 2896 10 6292
    cellular metabolic process 6.7219E-4 10 3033 10 6292
    gene expression 9.6759E-4 10 1283 7 6292
    metabolic process 1.0041E-3 10 3157 10 6292
    generation of catalytic spliceosome for first transesterification step 4.7611E-3 10 3 1 6292
    traversing start control point of mitotic cell cycle 9.5019E-3 10 6 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA binding 6.5031E-6 10 367 6 6292
    nucleic acid binding 1.9872E-4 10 666 6 6292
    binding 1.0216E-3 10 1294 7 6292
    RNA cap binding 3.1764E-3 10 2 1 6292
    5'-3' exoribonuclease activity 3.1764E-3 10 2 1 6292
    U5 snRNA binding 3.1764E-3 10 2 1 6292
    recombinase activity 6.3436E-3 10 4 1 6292
    snRNA binding 7.9239E-3 10 5 1 6292
    5'-3' exonuclease activity 9.5019E-3 10 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle