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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.4602E-13 10 101 8 6292
    cytosolic part 6.9153E-13 10 122 8 6292
    preribosome 3.2352E-12 10 34 6 6292
    ribosomal subunit 1.8849E-11 10 183 8 6292
    90S preribosome 1.8855E-11 10 17 5 6292
    cytosol 6.5103E-10 10 284 8 6292
    ribosome 7.6979E-10 10 290 8 6292
    ribonucleoprotein complex 1.4088E-9 10 514 9 6292
    cytosolic small ribosomal subunit 1.5082E-9 10 38 5 6292
    small ribosomal subunit 4.4091E-8 10 73 5 6292
    non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    intracellular non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    macromolecular complex 4.0767E-5 10 1635 9 6292
    cytosolic large ribosomal subunit 9.4349E-5 10 60 3 6292
    large ribosomal subunit 5.7057E-4 10 110 3 6292
    organelle part 6.1675E-3 10 2282 8 6292
    intracellular organelle part 6.1675E-3 10 2282 8 6292
    preribosome, small subunit precursor 9.5019E-3 10 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 5.1842E-13 10 376 10 6292
    cellular protein metabolic process 2.0277E-8 10 1074 10 6292
    protein metabolic process 3.5625E-8 10 1136 10 6292
    cellular macromolecule biosynthetic process 5.5363E-8 10 1187 10 6292
    macromolecule biosynthetic process 5.6306E-8 10 1189 10 6292
    gene expression 1.2084E-7 10 1283 10 6292
    cellular biosynthetic process 8.9828E-7 10 1567 10 6292
    biosynthetic process 1.121E-6 10 1602 10 6292
    cellular macromolecule metabolic process 3.9402E-5 10 2285 10 6292
    macromolecule metabolic process 5.1966E-5 10 2349 10 6292
    ribosomal subunit assembly 7.2637E-5 10 55 3 6292
    regulation of translation 8.0877E-5 10 57 3 6292
    posttranscriptional regulation of gene expression 9.9146E-5 10 61 3 6292
    ribosome assembly 1.1449E-4 10 64 3 6292
    regulation of cellular protein metabolic process 1.3725E-4 10 68 3 6292
    organelle assembly 1.4337E-4 10 69 3 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.757E-4 10 13 2 6292
    regulation of protein metabolic process 1.7664E-4 10 74 3 6292
    ribonucleoprotein complex assembly 3.3706E-4 10 92 3 6292
    primary metabolic process 4.2311E-4 10 2896 10 6292
    cellular metabolic process 6.7219E-4 10 3033 10 6292
    metabolic process 1.0041E-3 10 3157 10 6292
    ribosome biogenesis 1.4482E-3 10 346 4 6292
    ribosomal large subunit assembly 1.8038E-3 10 41 2 6292
    ribonucleoprotein complex biogenesis 1.9363E-3 10 374 4 6292
    cellular macromolecular complex assembly 2.4587E-3 10 182 3 6292
    maturation of SSU-rRNA 3.7066E-3 10 59 2 6292
    ribosomal large subunit biogenesis 4.4831E-3 10 65 2 6292
    cellular macromolecular complex subunit organization 6.671E-3 10 259 3 6292
    macromolecular complex assembly 8.3691E-3 10 281 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.531E-15 10 212 10 6292
    structural molecule activity 1.8156E-13 10 339 10 6292
    rRNA binding 2.6962E-4 10 16 2 6292
    RNA binding 1.8047E-3 10 367 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle