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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 16 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL12B, RPL12A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • regulation of translation
  • translational termination
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS30B, RPS30A
  • stress granule
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 2.5877E-19 16 101 12 6292
    cytosolic part 2.7827E-18 16 122 12 6292
    ribosomal subunit 4.2105E-16 16 183 12 6292
    ribonucleoprotein complex 5.1434E-14 16 514 14 6292
    cytosol 8.8267E-14 16 284 12 6292
    ribosome 1.1358E-13 16 290 12 6292
    cytosolic small ribosomal subunit 2.4614E-10 16 38 6 6292
    cytosolic large ribosomal subunit 4.331E-9 16 60 6 6292
    preribosome 1.4199E-8 16 34 5 6292
    small ribosomal subunit 1.4466E-8 16 73 6 6292
    90S preribosome 6.5086E-8 16 17 4 6292
    non-membrane-bounded organelle 1.4823E-7 16 959 12 6292
    intracellular non-membrane-bounded organelle 1.4823E-7 16 959 12 6292
    large ribosomal subunit 1.7297E-7 16 110 6 6292
    macromolecular complex 4.2472E-7 16 1635 14 6292
    organelle part 1.8408E-3 16 2282 12 6292
    intracellular organelle part 1.8408E-3 16 2282 12 6292
    stress granule 2.5429E-3 16 1 1 6292
    cytoplasmic part 4.2332E-3 16 2482 12 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.9504E-20 16 376 16 6292
    cellular protein metabolic process 4.7313E-13 16 1074 16 6292
    protein metabolic process 1.1685E-12 16 1136 16 6292
    cellular macromolecule biosynthetic process 2.3702E-12 16 1187 16 6292
    macromolecule biosynthetic process 2.4353E-12 16 1189 16 6292
    gene expression 8.2892E-12 16 1283 16 6292
    cellular biosynthetic process 2.0673E-10 16 1567 16 6292
    biosynthetic process 2.9487E-10 16 1602 16 6292
    regulation of translation 3.1522E-9 16 57 6 6292
    posttranscriptional regulation of gene expression 4.7969E-9 16 61 6 6292
    regulation of cellular protein metabolic process 9.3653E-9 16 68 6 6292
    regulation of protein metabolic process 1.5721E-8 16 74 6 6292
    cellular macromolecule metabolic process 8.851E-8 16 2285 16 6292
    macromolecule metabolic process 1.379E-7 16 2349 16 6292
    ribosomal subunit assembly 1.7214E-7 16 55 5 6292
    ribosome assembly 3.7233E-7 16 64 5 6292
    organelle assembly 5.4481E-7 16 69 5 6292
    ribonucleoprotein complex assembly 2.3047E-6 16 92 5 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8002E-6 16 13 3 6292
    primary metabolic process 3.9666E-6 16 2896 16 6292
    cellular metabolic process 8.3256E-6 16 3033 16 6292
    ribosome biogenesis 1.0639E-5 16 346 7 6292
    metabolic process 1.5832E-5 16 3157 16 6292
    ribonucleoprotein complex biogenesis 1.7765E-5 16 374 7 6292
    ribosomal small subunit biogenesis 3.3857E-5 16 26 3 6292
    cellular macromolecular complex assembly 6.46E-5 16 182 5 6292
    ribosomal large subunit assembly 1.3562E-4 16 41 3 6292
    cellular macromolecular complex subunit organization 3.4181E-4 16 259 5 6292
    maturation of SSU-rRNA 4.0219E-4 16 59 3 6292
    macromolecular complex assembly 4.9873E-4 16 281 5 6292
    regulation of gene expression 5.2571E-4 16 445 6 6292
    ribosomal large subunit biogenesis 5.3537E-4 16 65 3 6292
    ribosomal small subunit assembly 5.4201E-4 16 14 2 6292
    regulation of macromolecule biosynthetic process 5.9963E-4 16 456 6 6292
    regulation of cellular biosynthetic process 7.2154E-4 16 472 6 6292
    regulation of biosynthetic process 7.2977E-4 16 473 6 6292
    regulation of macromolecule metabolic process 8.6218E-4 16 488 6 6292
    cellular component biogenesis 9.0035E-4 16 694 7 6292
    regulation of primary metabolic process 1.1357E-3 16 514 6 6292
    regulation of cellular metabolic process 1.4164E-3 16 536 6 6292
    macromolecular complex subunit organization 1.484E-3 16 357 5 6292
    regulation of metabolic process 1.5757E-3 16 547 6 6292
    cellular component assembly 2.0794E-3 16 385 5 6292
    cellular process 3.565E-3 16 4426 16 6292
    rRNA processing 3.7938E-3 16 128 3 6292
    rRNA metabolic process 4.5942E-3 16 137 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.574E-24 16 212 16 6292
    structural molecule activity 3.587E-21 16 339 16 6292
    RNA binding 1.8355E-4 16 367 6 6292
    rRNA binding 7.1262E-4 16 16 2 6292
    nucleic acid binding 4.3373E-3 16 666 6 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle