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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL30
  • cytoplasm
  • negative regulation of nuclear mRNA splicing, via spliceosome
  • rRNA processing
  • negative regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS22A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 3.3436E-14 13 101 9 6292
    cytosolic part 1.9291E-13 13 122 9 6292
    ribosomal subunit 7.9273E-12 13 183 9 6292
    cytosol 4.1895E-10 13 284 9 6292
    ribosome 5.0523E-10 13 290 9 6292
    ribonucleoprotein complex 2.7819E-9 13 514 10 6292
    cytosolic large ribosomal subunit 8.0799E-8 13 60 5 6292
    cytosolic small ribosomal subunit 7.78E-7 13 38 4 6292
    large ribosomal subunit 1.7164E-6 13 110 5 6292
    90S preribosome 4.609E-6 13 17 3 6292
    small ribosomal subunit 1.1019E-5 13 73 4 6292
    non-membrane-bounded organelle 1.7148E-5 13 959 9 6292
    intracellular non-membrane-bounded organelle 1.7148E-5 13 959 9 6292
    preribosome 3.9744E-5 13 34 3 6292
    macromolecular complex 1.7639E-4 13 1635 10 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.0173E-16 13 376 13 6292
    cellular protein metabolic process 9.8294E-11 13 1074 13 6292
    protein metabolic process 2.047E-10 13 1136 13 6292
    cellular macromolecule biosynthetic process 3.6337E-10 13 1187 13 6292
    macromolecule biosynthetic process 3.7146E-10 13 1189 13 6292
    gene expression 1.0037E-9 13 1283 13 6292
    cellular biosynthetic process 1.3657E-8 13 1567 13 6292
    biosynthetic process 1.822E-8 13 1602 13 6292
    regulation of translation 6.2144E-8 13 57 5 6292
    posttranscriptional regulation of gene expression 8.7919E-8 13 61 5 6292
    regulation of cellular protein metabolic process 1.5291E-7 13 68 5 6292
    regulation of protein metabolic process 2.3478E-7 13 74 5 6292
    cellular macromolecule metabolic process 1.8698E-6 13 2285 13 6292
    macromolecule metabolic process 2.6802E-6 13 2349 13 6292
    primary metabolic process 4.1002E-5 13 2896 13 6292
    cellular metabolic process 7.4867E-5 13 3033 13 6292
    metabolic process 1.2617E-4 13 3157 13 6292
    ribosomal subunit assembly 1.6993E-4 13 55 3 6292
    ribosome assembly 2.6697E-4 13 64 3 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.0349E-4 13 13 2 6292
    organelle assembly 3.3372E-4 13 69 3 6292
    ribosome biogenesis 4.3563E-4 13 346 5 6292
    ribonucleoprotein complex biogenesis 6.2467E-4 13 374 5 6292
    ribonucleoprotein complex assembly 7.7815E-4 13 92 3 6292
    regulation of gene expression 1.383E-3 13 445 5 6292
    regulation of macromolecule biosynthetic process 1.5444E-3 13 456 5 6292
    regulation of cellular biosynthetic process 1.804E-3 13 472 5 6292
    regulation of biosynthetic process 1.8213E-3 13 473 5 6292
    rRNA processing 2.0259E-3 13 128 3 6292
    negative regulation of mRNA processing 2.0661E-3 13 1 1 6292
    negative regulation of nuclear mRNA splicing, via spliceosome 2.0661E-3 13 1 1 6292
    negative regulation of RNA splicing 2.0661E-3 13 1 1 6292
    regulation of macromolecule metabolic process 2.095E-3 13 488 5 6292
    rRNA metabolic process 2.4612E-3 13 137 3 6292
    regulation of primary metabolic process 2.6408E-3 13 514 5 6292
    ribosomal large subunit assembly 3.088E-3 13 41 2 6292
    regulation of cellular metabolic process 3.1797E-3 13 536 5 6292
    regulation of metabolic process 3.4778E-3 13 547 5 6292
    regulation of mRNA processing 4.1283E-3 13 2 1 6292
    regulation of RNA splicing 4.1283E-3 13 2 1 6292
    regulation of nuclear mRNA splicing, via spliceosome 4.1283E-3 13 2 1 6292
    cellular macromolecular complex assembly 5.4966E-3 13 182 3 6292
    maturation of SSU-rRNA 6.3097E-3 13 59 2 6292
    ribosomal large subunit biogenesis 7.6171E-3 13 65 2 6292
    ncRNA processing 8.7308E-3 13 215 3 6292
    cellular component biogenesis 9.7186E-3 13 694 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 5.0174E-20 13 212 13 6292
    structural molecule activity 2.5855E-17 13 339 13 6292
    rRNA binding 4.6527E-4 13 16 2 6292
    RNA binding 5.7247E-4 13 367 5 6292
    nucleic acid binding 8.1613E-3 13 666 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle