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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL4B
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    preribosome 8.3832E-10 10 34 5 6292
    cytosolic ribosome 2.9383E-9 10 101 6 6292
    90S preribosome 7.585E-9 10 17 4 6292
    cytosolic part 9.2635E-9 10 122 6 6292
    ribonucleoprotein complex 7.3162E-8 10 514 8 6292
    ribosomal subunit 1.0638E-7 10 183 6 6292
    cytosolic small ribosomal subunit 2.3149E-7 10 38 4 6292
    cytosol 1.4464E-6 10 284 6 6292
    ribosome 1.6359E-6 10 290 6 6292
    small ribosomal subunit 3.323E-6 10 73 4 6292
    non-membrane-bounded organelle 1.4707E-4 10 959 7 6292
    intracellular non-membrane-bounded organelle 1.4707E-4 10 959 7 6292
    macromolecular complex 5.4804E-4 10 1635 8 6292
    cytosolic large ribosomal subunit 3.8312E-3 10 60 2 6292
    preribosome, small subunit precursor 9.5019E-3 10 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 8.4087E-11 10 376 9 6292
    gene expression 1.2084E-7 10 1283 10 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.2018E-7 10 13 3 6292
    cellular protein metabolic process 1.0138E-6 10 1074 9 6292
    protein metabolic process 1.6655E-6 10 1136 9 6292
    cellular macromolecule biosynthetic process 2.4546E-6 10 1187 9 6292
    macromolecule biosynthetic process 2.4913E-6 10 1189 9 6292
    cellular biosynthetic process 2.8141E-5 10 1567 9 6292
    biosynthetic process 3.4126E-5 10 1602 9 6292
    cellular macromolecule metabolic process 3.9402E-5 10 2285 10 6292
    macromolecule metabolic process 5.1966E-5 10 2349 10 6292
    ribosomal subunit assembly 7.2637E-5 10 55 3 6292
    maturation of SSU-rRNA 8.9707E-5 10 59 3 6292
    ribosome biogenesis 9.789E-5 10 346 5 6292
    ribosome assembly 1.1449E-4 10 64 3 6292
    ribonucleoprotein complex biogenesis 1.4199E-4 10 374 5 6292
    organelle assembly 1.4337E-4 10 69 3 6292
    ribonucleoprotein complex assembly 3.3706E-4 10 92 3 6292
    primary metabolic process 4.2311E-4 10 2896 10 6292
    cellular metabolic process 6.7219E-4 10 3033 10 6292
    rRNA processing 8.8893E-4 10 128 3 6292
    metabolic process 1.0041E-3 10 3157 10 6292
    rRNA metabolic process 1.0834E-3 10 137 3 6292
    ribosomal large subunit assembly 1.8038E-3 10 41 2 6292
    cellular macromolecular complex assembly 2.4587E-3 10 182 3 6292
    cellular component biogenesis 2.5231E-3 10 694 5 6292
    regulation of translation 3.4634E-3 10 57 2 6292
    ncRNA processing 3.9518E-3 10 215 3 6292
    posttranscriptional regulation of gene expression 3.9577E-3 10 61 2 6292
    ribosomal large subunit biogenesis 4.4831E-3 10 65 2 6292
    regulation of cellular protein metabolic process 4.8974E-3 10 68 2 6292
    regulation of protein metabolic process 5.7773E-3 10 74 2 6292
    ncRNA metabolic process 6.5282E-3 10 257 3 6292
    cellular macromolecular complex subunit organization 6.671E-3 10 259 3 6292
    macromolecular complex assembly 8.3691E-3 10 281 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.6009E-13 10 212 9 6292
    structural molecule activity 3.2934E-11 10 339 9 6292
    RNA binding 1.8047E-3 10 367 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle