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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL12B, RPL12A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • regulation of translation
  • translational termination
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL30
  • cytoplasm
  • negative regulation of nuclear mRNA splicing, via spliceosome
  • rRNA processing
  • negative regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS22A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • RPS30B, RPS30A
  • stress granule
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 4.797E-21 17 101 13 6292
    cytosolic part 6.3752E-20 17 122 13 6292
    ribosomal subunit 1.4992E-17 17 183 13 6292
    cytosol 4.9973E-15 17 284 13 6292
    ribosome 6.5721E-15 17 290 13 6292
    ribonucleoprotein complex 2.6981E-13 17 514 14 6292
    cytosolic small ribosomal subunit 3.0445E-12 17 38 7 6292
    small ribosomal subunit 3.7425E-10 17 73 7 6292
    cytosolic large ribosomal subunit 6.6441E-9 17 60 6 6292
    non-membrane-bounded organelle 2.9132E-8 17 959 13 6292
    intracellular non-membrane-bounded organelle 2.9132E-8 17 959 13 6292
    90S preribosome 8.4972E-8 17 17 4 6292
    large ribosomal subunit 2.6353E-7 17 110 6 6292
    preribosome 1.6097E-6 17 34 4 6292
    macromolecular complex 1.8283E-6 17 1635 14 6292
    organelle part 8.5928E-4 17 2282 13 6292
    intracellular organelle part 8.5928E-4 17 2282 13 6292
    cytoplasmic part 2.1458E-3 17 2482 13 6292
    stress granule 2.7018E-3 17 1 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.1188E-21 17 376 17 6292
    cellular protein metabolic process 7.9759E-14 17 1074 17 6292
    protein metabolic process 2.0853E-13 17 1136 17 6292
    cellular macromolecule biosynthetic process 4.4224E-13 17 1187 17 6292
    macromolecule biosynthetic process 4.5517E-13 17 1189 17 6292
    gene expression 1.6734E-12 17 1283 17 6292
    cellular biosynthetic process 5.109E-11 17 1567 17 6292
    regulation of translation 6.2106E-11 17 57 7 6292
    biosynthetic process 7.4517E-11 17 1602 17 6292
    posttranscriptional regulation of gene expression 1.0191E-10 17 61 7 6292
    regulation of cellular protein metabolic process 2.2424E-10 17 68 7 6292
    regulation of protein metabolic process 4.1277E-10 17 74 7 6292
    cellular macromolecule metabolic process 3.1999E-8 17 2285 17 6292
    macromolecule metabolic process 5.1262E-8 17 2349 17 6292
    ribosomal subunit assembly 2.4225E-7 17 55 5 6292
    ribosome assembly 5.2335E-7 17 64 5 6292
    organelle assembly 7.6527E-7 17 69 5 6292
    ribosome biogenesis 1.212E-6 17 346 8 6292
    primary metabolic process 1.8202E-6 17 2896 17 6292
    ribonucleoprotein complex biogenesis 2.1895E-6 17 374 8 6292
    ribonucleoprotein complex assembly 3.2275E-6 17 92 5 6292
    cellular metabolic process 4.0023E-6 17 3033 17 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.609E-6 17 13 3 6292
    metabolic process 7.9234E-6 17 3157 17 6292
    ribosomal small subunit biogenesis 4.1E-5 17 26 3 6292
    regulation of gene expression 8.8035E-5 17 445 7 6292
    cellular macromolecular complex assembly 8.9383E-5 17 182 5 6292
    regulation of macromolecule biosynthetic process 1.0289E-4 17 456 7 6292
    regulation of cellular biosynthetic process 1.2814E-4 17 472 7 6292
    regulation of biosynthetic process 1.2987E-4 17 473 7 6292
    regulation of macromolecule metabolic process 1.5827E-4 17 488 7 6292
    ribosomal large subunit assembly 1.6394E-4 17 41 3 6292
    cellular component biogenesis 2.0599E-4 17 694 8 6292
    regulation of primary metabolic process 2.1952E-4 17 514 7 6292
    regulation of cellular metabolic process 2.854E-4 17 536 7 6292
    rRNA processing 3.167E-4 17 128 4 6292
    regulation of metabolic process 3.2394E-4 17 547 7 6292
    rRNA metabolic process 4.1071E-4 17 137 4 6292
    cellular macromolecular complex subunit organization 4.6809E-4 17 259 5 6292
    maturation of SSU-rRNA 4.8512E-4 17 59 3 6292
    ribosomal small subunit assembly 6.135E-4 17 14 2 6292
    ribosomal large subunit biogenesis 6.4531E-4 17 65 3 6292
    macromolecular complex assembly 6.8097E-4 17 281 5 6292
    biological regulation 1.9436E-3 17 1213 9 6292
    macromolecular complex subunit organization 2.0056E-3 17 357 5 6292
    ncRNA processing 2.222E-3 17 215 4 6292
    cellular process 2.5051E-3 17 4426 17 6292
    negative regulation of mRNA processing 2.7018E-3 17 1 1 6292
    negative regulation of nuclear mRNA splicing, via spliceosome 2.7018E-3 17 1 1 6292
    negative regulation of RNA splicing 2.7018E-3 17 1 1 6292
    cellular component assembly 2.7998E-3 17 385 5 6292
    regulation of cellular process 3.1119E-3 17 796 7 6292
    regulation of biological process 3.8007E-3 17 824 7 6292
    ncRNA metabolic process 4.2474E-3 17 257 4 6292
    regulation of mRNA processing 5.3968E-3 17 2 1 6292
    regulation of RNA splicing 5.3968E-3 17 2 1 6292
    regulation of nuclear mRNA splicing, via spliceosome 5.3968E-3 17 2 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.9155E-26 17 212 17 6292
    structural molecule activity 1.8461E-22 17 339 17 6292
    RNA binding 2.6984E-4 17 367 6 6292
    rRNA binding 8.0644E-4 17 16 2 6292
    nucleic acid binding 6.1125E-3 17 666 6 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle