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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.3542E-17 15 101 11 6292
    cytosolic part 1.1808E-16 15 122 11 6292
    ribosomal subunit 1.1533E-14 15 183 11 6292
    ribonucleoprotein complex 5.6435E-13 15 514 13 6292
    cytosol 1.524E-12 15 284 11 6292
    ribosome 1.9189E-12 15 290 11 6292
    cytosolic large ribosomal subunit 3.0339E-11 15 60 7 6292
    large ribosomal subunit 2.363E-9 15 110 7 6292
    preribosome 9.7994E-9 15 34 5 6292
    90S preribosome 4.8896E-8 15 17 4 6292
    non-membrane-bounded organelle 7.3959E-7 15 959 11 6292
    intracellular non-membrane-bounded organelle 7.3959E-7 15 959 11 6292
    macromolecular complex 1.443E-6 15 1635 13 6292
    cytosolic small ribosomal subunit 1.4725E-6 15 38 4 6292
    small ribosomal subunit 2.067E-5 15 73 4 6292
    organelle part 3.8752E-3 15 2282 11 6292
    intracellular organelle part 3.8752E-3 15 2282 11 6292
    cytoplasmic part 8.2094E-3 15 2482 11 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 3.3913E-19 15 376 15 6292
    cellular protein metabolic process 2.8044E-12 15 1074 15 6292
    protein metabolic process 6.5431E-12 15 1136 15 6292
    cellular macromolecule biosynthetic process 1.2694E-11 15 1187 15 6292
    macromolecule biosynthetic process 1.3021E-11 15 1189 15 6292
    gene expression 4.1034E-11 15 1283 15 6292
    cellular biosynthetic process 8.3612E-10 15 1567 15 6292
    biosynthetic process 1.1663E-9 15 1602 15 6292
    ribosomal subunit assembly 1.1913E-7 15 55 5 6292
    cellular macromolecule metabolic process 2.4475E-7 15 2285 15 6292
    ribosome assembly 2.58E-7 15 64 5 6292
    macromolecule metabolic process 3.7086E-7 15 2349 15 6292
    organelle assembly 3.7776E-7 15 69 5 6292
    ribonucleoprotein complex assembly 1.6029E-6 15 92 5 6292
    primary metabolic process 8.6423E-6 15 2896 15 6292
    cellular metabolic process 1.7316E-5 15 3033 15 6292
    metabolic process 3.1628E-5 15 3157 15 6292
    cellular macromolecular complex assembly 4.5473E-5 15 182 5 6292
    ribosome biogenesis 8.677E-5 15 346 6 6292
    ribosomal large subunit assembly 1.1069E-4 15 41 3 6292
    ribonucleoprotein complex biogenesis 1.3398E-4 15 374 6 6292
    cellular macromolecular complex subunit organization 2.4311E-4 15 259 5 6292
    regulation of translation 2.9694E-4 15 57 3 6292
    maturation of SSU-rRNA 3.2896E-4 15 59 3 6292
    macromolecular complex assembly 3.5576E-4 15 281 5 6292
    posttranscriptional regulation of gene expression 3.6315E-4 15 61 3 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.0759E-4 15 13 2 6292
    ribosomal large subunit biogenesis 4.3822E-4 15 65 3 6292
    ribosomal small subunit assembly 4.7486E-4 15 14 2 6292
    regulation of cellular protein metabolic process 5.0063E-4 15 68 3 6292
    regulation of protein metabolic process 6.42E-4 15 74 3 6292
    macromolecular complex subunit organization 1.0695E-3 15 357 5 6292
    cellular component assembly 1.5042E-3 15 385 5 6292
    ribosomal small subunit biogenesis 1.6681E-3 15 26 2 6292
    response to cycloheximide 2.384E-3 15 1 1 6292
    response to cycloalkane 2.384E-3 15 1 1 6292
    response to organic cyclic substance 2.384E-3 15 1 1 6292
    rRNA processing 3.1286E-3 15 128 3 6292
    cellular component biogenesis 3.6715E-3 15 694 6 6292
    rRNA metabolic process 3.7927E-3 15 137 3 6292
    cellular process 5.0732E-3 15 4426 15 6292
    response to antibiotic 7.136E-3 15 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 5.0151E-23 15 212 15 6292
    structural molecule activity 6.9493E-20 15 339 15 6292
    rRNA binding 6.2447E-4 15 16 2 6292
    RNA binding 1.2121E-3 15 367 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle