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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
HCA4
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ATP-dependent RNA helicase activity
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    90S preribosome 9.1004E-7 8 17 3 6292
    cytosolic ribosome 4.1685E-6 8 101 4 6292
    preribosome 7.9274E-6 8 34 3 6292
    cytosolic part 8.871E-6 8 122 4 6292
    cytosolic small ribosomal subunit 1.1149E-5 8 38 3 6292
    non-membrane-bounded organelle 1.3016E-5 8 959 7 6292
    intracellular non-membrane-bounded organelle 1.3016E-5 8 959 7 6292
    ribosomal subunit 4.4245E-5 8 183 4 6292
    small ribosomal subunit 8.0492E-5 8 73 3 6292
    ribonucleoprotein complex 1.6235E-4 8 514 5 6292
    cytosol 2.4634E-4 8 284 4 6292
    ribosome 2.671E-4 8 290 4 6292
    nucleolus 1.8378E-3 8 211 3 6292
    intracellular organelle part 4.4856E-3 8 2282 7 6292
    organelle part 4.4856E-3 8 2282 7 6292
    nuclear outer membrane 4.9014E-3 8 86 2 6292
    nuclear membrane 6.2001E-3 8 97 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8367E-7 8 13 3 6292
    ribosome biogenesis 6.7573E-7 8 346 6 6292
    ribonucleoprotein complex biogenesis 1.0727E-6 8 374 6 6292
    translation 3.5782E-5 8 376 5 6292
    regulation of translation 3.8233E-5 8 57 3 6292
    cellular component biogenesis 4.0619E-5 8 694 6 6292
    maturation of SSU-rRNA 4.2427E-5 8 59 3 6292
    posttranscriptional regulation of gene expression 4.6914E-5 8 61 3 6292
    regulation of cellular protein metabolic process 6.5054E-5 8 68 3 6292
    regulation of protein metabolic process 8.3843E-5 8 74 3 6292
    rRNA processing 4.2742E-4 8 128 3 6292
    rRNA metabolic process 5.2205E-4 8 137 3 6292
    gene expression 1.3613E-3 8 1283 6 6292
    ncRNA processing 1.9402E-3 8 215 3 6292
    ncRNA metabolic process 3.2376E-3 8 257 3 6292
    cellular protein metabolic process 5.103E-3 8 1074 5 6292
    protein metabolic process 6.5695E-3 8 1136 5 6292
    cellular macromolecule biosynthetic process 7.9943E-3 8 1187 5 6292
    macromolecule biosynthetic process 8.0545E-3 8 1189 5 6292
    RNA processing 9.7426E-3 8 380 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 2.1368E-6 8 212 5 6292
    structural molecule activity 2.1584E-5 8 339 5 6292
    rRNA binding 1.6826E-4 8 16 2 6292
    RNA binding 6.6069E-4 8 367 4 6292
    nucleic acid binding 6.1432E-3 8 666 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle