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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • MAK5
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    90S preribosome 4.5585E-9 9 17 4 6292
    preribosome 8.7868E-8 9 34 4 6292
    cytosolic ribosome 1.1557E-7 9 101 5 6292
    cytosolic small ribosomal subunit 1.395E-7 9 38 4 6292
    cytosolic part 2.9904E-7 9 122 5 6292
    ribonucleoprotein complex 7.2713E-7 9 514 7 6292
    small ribosomal subunit 2.0114E-6 9 73 4 6292
    ribosomal subunit 2.2594E-6 9 183 5 6292
    cytosol 1.9632E-5 9 284 5 6292
    ribosome 2.174E-5 9 290 5 6292
    non-membrane-bounded organelle 5.0826E-5 9 959 7 6292
    intracellular non-membrane-bounded organelle 5.0826E-5 9 959 7 6292
    macromolecular complex 1.7084E-3 9 1635 7 6292
    small nucleolar ribonucleoprotein complex 4.4137E-3 9 72 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 8.3629E-8 9 376 7 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.7481E-7 9 13 3 6292
    gene expression 5.9596E-7 9 1283 9 6292
    rRNA processing 1.903E-5 9 128 4 6292
    rRNA metabolic process 2.4907E-5 9 137 4 6292
    regulation of translation 5.698E-5 9 57 3 6292
    maturation of SSU-rRNA 6.3216E-5 9 59 3 6292
    posttranscriptional regulation of gene expression 6.9885E-5 9 61 3 6292
    regulation of cellular protein metabolic process 9.6826E-5 9 68 3 6292
    cellular protein metabolic process 1.0846E-4 9 1074 7 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    regulation of protein metabolic process 1.247E-4 9 74 3 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    ncRNA processing 1.4596E-4 9 215 4 6292
    protein metabolic process 1.5759E-4 9 1136 7 6292
    cellular macromolecule biosynthetic process 2.1089E-4 9 1187 7 6292
    macromolecule biosynthetic process 2.1326E-4 9 1189 7 6292
    ncRNA metabolic process 2.9128E-4 9 257 4 6292
    ribosome biogenesis 9.0809E-4 9 346 4 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    ribonucleoprotein complex biogenesis 1.2185E-3 9 374 4 6292
    RNA processing 1.2938E-3 9 380 4 6292
    cellular biosynthetic process 1.2993E-3 9 1567 7 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    biosynthetic process 1.4983E-3 9 1602 7 6292
    metabolic process 2.004E-3 9 3157 9 6292
    ribosomal subunit assembly 2.5969E-3 9 55 2 6292
    ribosome assembly 3.502E-3 9 64 2 6292
    organelle assembly 4.0601E-3 9 69 2 6292
    ribonucleoprotein complex assembly 7.1217E-3 9 92 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.0532E-7 9 212 6 6292
    structural molecule activity 1.7138E-6 9 339 6 6292
    rRNA binding 2.1602E-4 9 16 2 6292
    RNA binding 1.1347E-3 9 367 4 6292
    nucleic acid binding 1.1464E-3 9 666 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle