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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • IMD1
    RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPL4B
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPP0
  • ribosomal large subunit assembly
  • translational elongation
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    preribosome 4.2322E-9 13 34 5 6292
    90S preribosome 2.5697E-8 13 17 4 6292
    cytosolic small ribosomal subunit 7.78E-7 13 38 4 6292
    cytosolic ribosome 1.1216E-6 13 101 5 6292
    ribonucleoprotein complex 1.6755E-6 13 514 8 6292
    cytosolic part 2.8697E-6 13 122 5 6292
    small ribosomal subunit 1.1019E-5 13 73 4 6292
    ribosomal subunit 2.0983E-5 13 183 5 6292
    cytosol 1.7262E-4 13 284 5 6292
    ribosome 1.9052E-4 13 290 5 6292
    macromolecular complex 7.225E-3 13 1635 8 6292
    non-membrane-bounded organelle 8.0908E-3 13 959 6 6292
    intracellular non-membrane-bounded organelle 8.0908E-3 13 959 6 6292
    small nucleolar ribonucleoprotein complex 9.2843E-3 13 72 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 2.1116E-12 13 376 11 6292
    gene expression 5.2425E-8 13 1283 12 6292
    cellular protein metabolic process 1.9126E-7 13 1074 11 6292
    protein metabolic process 3.4803E-7 13 1136 11 6292
    cellular macromolecule biosynthetic process 5.5534E-7 13 1187 11 6292
    macromolecule biosynthetic process 5.6537E-7 13 1189 11 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.9478E-6 13 13 3 6292
    cellular biosynthetic process 1.038E-5 13 1567 11 6292
    biosynthetic process 1.3071E-5 13 1602 11 6292
    cellular macromolecule metabolic process 4.4721E-5 13 2285 12 6292
    macromolecule metabolic process 6.1467E-5 13 2349 12 6292
    maturation of SSU-rRNA 2.0956E-4 13 59 3 6292
    ribosome biogenesis 4.3563E-4 13 346 5 6292
    ribonucleoprotein complex biogenesis 6.2467E-4 13 374 5 6292
    primary metabolic process 6.6865E-4 13 2896 12 6292
    cellular metabolic process 1.1248E-3 13 3033 12 6292
    metabolic process 1.7612E-3 13 3157 12 6292
    rRNA processing 2.0259E-3 13 128 3 6292
    rRNA metabolic process 2.4612E-3 13 137 3 6292
    ribosomal subunit assembly 5.5019E-3 13 55 2 6292
    regulation of translation 5.8994E-3 13 57 2 6292
    posttranscriptional regulation of gene expression 6.7329E-3 13 61 2 6292
    ribosome assembly 7.3913E-3 13 64 2 6292
    regulation of cellular protein metabolic process 8.3131E-3 13 68 2 6292
    organelle assembly 8.5513E-3 13 69 2 6292
    ncRNA processing 8.7308E-3 13 215 3 6292
    cellular component biogenesis 9.7186E-3 13 694 5 6292
    regulation of protein metabolic process 9.7882E-3 13 74 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.0059E-13 13 212 10 6292
    structural molecule activity 4.4859E-11 13 339 10 6292
    rRNA binding 4.6527E-4 13 16 2 6292
    RNA binding 5.3427E-3 13 367 4 6292
    nucleic acid binding 8.1613E-3 13 666 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle