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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
FUN12
  • mitochondrion
  • translational initiation
  • translation initiation factor activity
  • GTPase activity
  • IMD1
    KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPP0
  • ribosomal large subunit assembly
  • translational elongation
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS6A, RPS6B
  • small-subunit processome
  • nucleus
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • nucleolus
  • 90S preribosome
  • intracellular
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • translation
  • structural constituent of ribosome
  • RPS7A
  • small nucleolar ribonucleoprotein complex
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    preribosome 2.6145E-9 12 34 5 6292
    90S preribosome 1.782E-8 12 17 4 6292
    cytosolic small ribosomal subunit 5.4096E-7 12 38 4 6292
    cytosolic ribosome 6.9907E-7 12 101 5 6292
    cytosolic part 1.7937E-6 12 122 5 6292
    small ribosomal subunit 7.696E-6 12 73 4 6292
    ribonucleoprotein complex 1.2852E-5 12 514 7 6292
    ribosomal subunit 1.3223E-5 12 183 5 6292
    cytosol 1.1027E-4 12 284 5 6292
    ribosome 1.2181E-4 12 290 5 6292
    non-membrane-bounded organelle 4.9929E-3 12 959 6 6292
    intracellular non-membrane-bounded organelle 4.9929E-3 12 959 6 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 3.0688E-11 12 376 10 6292
    cellular protein metabolic process 9.5815E-7 12 1074 10 6292
    protein metabolic process 1.6479E-6 12 1136 10 6292
    cellular macromolecule biosynthetic process 2.516E-6 12 1187 10 6292
    macromolecule biosynthetic process 2.5571E-6 12 1189 10 6292
    gene expression 5.3098E-6 12 1283 10 6292
    cellular biosynthetic process 3.5603E-5 12 1567 10 6292
    biosynthetic process 4.3855E-5 12 1602 10 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.571E-4 12 13 2 6292
    ribosome biogenesis 2.8065E-4 12 346 5 6292
    ribonucleoprotein complex biogenesis 4.0398E-4 12 374 5 6292
    cellular macromolecule metabolic process 1.1724E-3 12 2285 10 6292
    macromolecule metabolic process 1.504E-3 12 2349 10 6292
    ribosomal subunit assembly 4.6816E-3 12 55 2 6292
    regulation of translation 5.0209E-3 12 57 2 6292
    maturation of SSU-rRNA 5.3712E-3 12 59 2 6292
    posttranscriptional regulation of gene expression 5.7327E-3 12 61 2 6292
    ribosome assembly 6.2953E-3 12 64 2 6292
    cellular component biogenesis 6.5683E-3 12 694 5 6292
    regulation of cellular protein metabolic process 7.0833E-3 12 68 2 6292
    organelle assembly 7.2871E-3 12 69 2 6292
    regulation of protein metabolic process 8.3454E-3 12 74 2 6292
    primary metabolic process 9.5102E-3 12 2896 10 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 9.542E-12 12 212 9 6292
    structural molecule activity 6.577E-10 12 339 9 6292
    rRNA binding 3.9428E-4 12 16 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle